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Page 1
Antibody Levels from High-Throughput Variant-Specific SARS-CoV-2 Anti-Spike IgG and ACE2 Neutralization Assays Correlate with COVID Infection Risk in a Large Population.
Jacobs MB, Clark AE, Goldhaber NH, Valentine HD, Rivera A, Ngo T, Barber T, Holmes J, Manfredi B, Garretson AF, Bray W, Knight R, Longhurst CA, Carlin AF, De Hoff P, Laurent LC. Jacobs MB, et al. Among authors: garretson af. J Infect Dis. 2024 Dec 16:jiae622. doi: 10.1093/infdis/jiae622. Online ahead of print. J Infect Dis. 2024. PMID: 39676529
Oral pharmacokinetics and efficacy of oral phospholipid remdesivir nucleoside prodrugs against SARS-CoV-2 in mice.
Carlin AF, Beadle JR, Ardanuy J, Clark AE, Rhodes V, Garretson AF, Murphy JA, Valiaeva N, Schooley RT, Frieman MB, Hostetler KY. Carlin AF, et al. Among authors: garretson af. Antimicrob Agents Chemother. 2024 Oct 8;68(10):e0103924. doi: 10.1128/aac.01039-24. Epub 2024 Sep 6. Antimicrob Agents Chemother. 2024. PMID: 39240093 Free PMC article.
Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs.
McMillan RE, Lo MK, Zhang XQ, Beadle JR, Valiaeva N, Garretson AF, Clark AE, Freshman JE, Murphy J, Montgomery JM, Spiropoulou CF, Schooley RT, Hostetler KY, Carlin AF. McMillan RE, et al. Among authors: garretson af. Antiviral Res. 2023 Nov;219:105718. doi: 10.1016/j.antiviral.2023.105718. Epub 2023 Sep 25. Antiviral Res. 2023. PMID: 37758067 Free PMC article.
Neutralizing Antibody Responses After Severe Acute Respiratory Syndrome Coronavirus 2 BA.2 and BA.2.12.1 Infection Do Not Neutralize BA.4 and BA.5 and Can Be Blunted by Nirmatrelvir/Ritonavir Treatment.
Carlin AF, Clark AE, Garretson AF, Bray W, Porrachia M, Santos AT, Rana TM, Chaillon A, Smith DM. Carlin AF, et al. Among authors: garretson af. Open Forum Infect Dis. 2023 Mar 21;10(4):ofad154. doi: 10.1093/ofid/ofad154. eCollection 2023 Apr. Open Forum Infect Dis. 2023. PMID: 37096144 Free PMC article.
1-O-Octadecyl-2-O-benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity.
Carlin AF, Beadle JR, Clark AE, Gully KL, Moreira FR, Baric RS, Graham RL, Valiaeva N, Leibel SL, Bray W, McMillan RE, Freshman JE, Garretson AF, McVicar RN, Rana T, Zhang XQ, Murphy JA, Schooley RT, Hostetler KY. Carlin AF, et al. Among authors: garretson af. J Med Chem. 2023 Apr 27;66(8):5802-5819. doi: 10.1021/acs.jmedchem.3c00046. Epub 2023 Apr 11. J Med Chem. 2023. PMID: 37040439 Free PMC article.
Identification of global inhibitors of cellular glycosylation.
Sørensen DM, Büll C, Madsen TD, Lira-Navarrete E, Clausen TM, Clark AE, Garretson AF, Karlsson R, Pijnenborg JFA, Yin X, Miller RL, Chanda SK, Boltje TJ, Schjoldager KT, Vakhrushev SY, Halim A, Esko JD, Carlin AF, Hurtado-Guerrero R, Weigert R, Clausen H, Narimatsu Y. Sørensen DM, et al. Among authors: garretson af. Nat Commun. 2023 Feb 20;14(1):948. doi: 10.1038/s41467-023-36598-7. Nat Commun. 2023. PMID: 36804936 Free PMC article.
SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus.
Branche E, Wang YT, Viramontes KM, Valls Cuevas JM, Xie J, Ana-Sosa-Batiz F, Shafee N, Duttke SH, McMillan RE, Clark AE, Nguyen MN, Garretson AF, Crames JJ, Spann NJ, Zhu Z, Rich JN, Spector DH, Benner C, Shresta S, Carlin AF. Branche E, et al. Among authors: garretson af. Nat Commun. 2022 Sep 12;13(1):5341. doi: 10.1038/s41467-022-33041-1. Nat Commun. 2022. PMID: 36097162 Free PMC article.
18 results