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702 results

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Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche.
Davis H, Irshad S, Bansal M, Rafferty H, Boitsova T, Bardella C, Jaeger E, Lewis A, Freeman-Mills L, Giner FC, Rodenas-Cuadrado P, Mallappa S, Clark S, Thomas H, Jeffery R, Poulsom R, Rodriguez-Justo M, Novelli M, Chetty R, Silver A, Sansom OJ, Greten FR, Wang LM, East JE, Tomlinson I, Leedham SJ. Davis H, et al. Among authors: silver a. Nat Med. 2015 Jan;21(1):62-70. doi: 10.1038/nm.3750. Epub 2014 Dec 1. Nat Med. 2015. PMID: 25419707 Free PMC article.
An update on the genetics of colorectal cancer.
Kemp Z, Thirlwell C, Sieber O, Silver A, Tomlinson I. Kemp Z, et al. Among authors: silver a. Hum Mol Genet. 2004 Oct 1;13 Spec No 2:R177-85. doi: 10.1093/hmg/ddh247. Hum Mol Genet. 2004. PMID: 15358723 Review.
Evidence for an association between compound heterozygosity for germ line mutations in the hemochromatosis (HFE) gene and increased risk of colorectal cancer.
Robinson JP, Johnson VL, Rogers PA, Houlston RS, Maher ER, Bishop DT, Evans DG, Thomas HJ, Tomlinson IP, Silver AR. Robinson JP, et al. Among authors: silver ar. Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1460-3. doi: 10.1158/1055-9965.EPI-04-0672. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 15941956
Refining molecular analysis in the pathways of colorectal carcinogenesis.
Rowan A, Halford S, Gaasenbeek M, Kemp Z, Sieber O, Volikos E, Douglas E, Fiegler H, Carter N, Talbot I, Silver A, Tomlinson I. Rowan A, et al. Among authors: silver a. Clin Gastroenterol Hepatol. 2005 Nov;3(11):1115-23. doi: 10.1016/s1542-3565(05)00618-x. Clin Gastroenterol Hepatol. 2005. PMID: 16271343
Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation.
Sieber OM, Segditsas S, Knudsen AL, Zhang J, Luz J, Rowan AJ, Spain SL, Thirlwell C, Howarth KM, Jaeger EE, Robinson J, Volikos E, Silver A, Kelly G, Aretz S, Frayling I, Hutter P, Dunlop M, Guenther T, Neale K, Phillips R, Heinimann K, Tomlinson IP. Sieber OM, et al. Among authors: silver a. Gut. 2006 Oct;55(10):1440-8. doi: 10.1136/gut.2005.087106. Epub 2006 Feb 4. Gut. 2006. PMID: 16461775 Free PMC article.
702 results