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Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus.
Uchida H, Marzulli M, Nakano K, Goins WF, Chan J, Hong CS, Mazzacurati L, Yoo JY, Haseley A, Nakashima H, Baek H, Kwon H, Kumagai I, Kuroki M, Kaur B, Chiocca EA, Grandi P, Cohen JB, Glorioso JC. Uchida H, et al. Among authors: goins wf. Mol Ther. 2013 Mar;21(3):561-9. doi: 10.1038/mt.2012.211. Epub 2012 Oct 16. Mol Ther. 2013. PMID: 23070115 Free PMC article.
Use of miRNA response sequences to block off-target replication and increase the safety of an unattenuated, glioblastoma-targeted oncolytic HSV.
Mazzacurati L, Marzulli M, Reinhart B, Miyagawa Y, Uchida H, Goins WF, Li A, Kaur B, Caligiuri M, Cripe T, Chiocca EA, Amankulor N, Cohen JB, Glorioso JC, Grandi P. Mazzacurati L, et al. Among authors: goins wf. Mol Ther. 2015 Jan;23(1):99-107. doi: 10.1038/mt.2014.177. Epub 2014 Sep 9. Mol Ther. 2015. PMID: 25200130 Free PMC article.
Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma.
Nakashima H, Kaufmann JK, Wang PY, Nguyen T, Speranza MC, Kasai K, Okemoto K, Otsuki A, Nakano I, Fernandez S, Goins WF, Grandi P, Glorioso JC, Lawler S, Cripe TP, Chiocca EA. Nakashima H, et al. Among authors: goins wf. J Clin Invest. 2015 Nov 2;125(11):4269-80. doi: 10.1172/JCI80713. Epub 2015 Oct 20. J Clin Invest. 2015. PMID: 26524593 Free PMC article.
Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma.
Nakashima H, Nguyen T, Kasai K, Passaro C, Ito H, Goins WF, Shaikh I, Erdelyi R, Nishihara R, Nakano I, Reardon DA, Anderson AC, Kuchroo V, Chiocca EA. Nakashima H, et al. Among authors: goins wf. Clin Cancer Res. 2018 Jun 1;24(11):2574-2584. doi: 10.1158/1078-0432.CCR-17-2954. Epub 2018 Mar 6. Clin Cancer Res. 2018. PMID: 29511029 Free PMC article.
Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy.
Passaro C, Alayo Q, De Laura I, McNulty J, Grauwet K, Ito H, Bhaskaran V, Mineo M, Lawler SE, Shah K, Speranza MC, Goins W, McLaughlin E, Fernandez S, Reardon DA, Freeman GJ, Chiocca EA, Nakashima H. Passaro C, et al. Clin Cancer Res. 2019 Jan 1;25(1):290-299. doi: 10.1158/1078-0432.CCR-18-2311. Epub 2018 Oct 2. Clin Cancer Res. 2019. PMID: 30279232 Free PMC article.
Correction: Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy.
Passaro C, Alayo Q, DeLaura I, McNulty J, Grauwet K, Ito H, Bhaskaran V, Mineo M, Lawler SE, Shah K, Speranza MC, Goins W, McLaughlin E, Fernandez S, Reardon DA, Freeman GJ, Chiocca EA, Nakashima H. Passaro C, et al. Clin Cancer Res. 2020 Feb 1;26(3):758. doi: 10.1158/1078-0432.CCR-19-4091. Clin Cancer Res. 2020. PMID: 32014888 No abstract available.
Oncolytic HSV Vectors and Anti-Tumor Immunity.
Glorioso JC, Cohen JB, Goins WF, Hall B, Jackson JW, Kohanbash G, Amankulor N, Kaur B, Caligiuri MA, Chiocca EA, Holland EC, Quéva C. Glorioso JC, et al. Among authors: goins wf. Curr Issues Mol Biol. 2021;41:381-468. doi: 10.21775/cimb.041.381. Epub 2020 Sep 17. Curr Issues Mol Biol. 2021. PMID: 32938804 Free article. Review.
125 results