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Page 1
Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis.
Griess K, Rieck M, Müller N, Karsai G, Hartwig S, Pelligra A, Hardt R, Schlegel C, Kuboth J, Uhlemeyer C, Trenkamp S, Jeruschke K, Weiss J, Peifer-Weiss L, Xu W, Cames S, Yi X, Cnop M, Beller M, Stark H, Kondadi AK, Reichert AS, Markgraf D, Wammers M, Häussinger D, Kuss O, Lehr S, Eizirik D, Lickert H, Lammert E, Roden M, Winter D, Al-Hasani H, Höglinger D, Hornemann T, Brüning JC, Belgardt BF. Griess K, et al. Among authors: hornemann t. Nat Cell Biol. 2023 Jan;25(1):20-29. doi: 10.1038/s41556-022-01027-2. Epub 2022 Dec 21. Nat Cell Biol. 2023. PMID: 36543979 Free PMC article.
Deoxysphingoid bases as plasma markers in diabetes mellitus.
Bertea M, Rütti MF, Othman A, Marti-Jaun J, Hersberger M, von Eckardstein A, Hornemann T. Bertea M, et al. Among authors: hornemann t. Lipids Health Dis. 2010 Aug 16;9:84. doi: 10.1186/1476-511X-9-84. Lipids Health Dis. 2010. PMID: 20712864 Free PMC article.
Novel Mouse Models of Methylmalonic Aciduria Recapitulate Phenotypic Traits with a Genetic Dosage Effect.
Forny P, Schumann A, Mustedanagic M, Mathis D, Wulf MA, Nägele N, Langhans CD, Zhakupova A, Heeren J, Scheja L, Fingerhut R, Peters HL, Hornemann T, Thony B, Kölker S, Burda P, Froese DS, Devuyst O, Baumgartner MR. Forny P, et al. Among authors: hornemann t. J Biol Chem. 2016 Sep 23;291(39):20563-73. doi: 10.1074/jbc.M116.747717. Epub 2016 Aug 12. J Biol Chem. 2016. PMID: 27519416 Free PMC article.
ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase.
Zhakupova A, Debeuf N, Krols M, Toussaint W, Vanhoutte L, Alecu I, Kutalik Z, Vollenweider P, Ernst D, von Eckardstein A, Lambrecht BN, Janssens S, Hornemann T. Zhakupova A, et al. Among authors: hornemann t. FASEB J. 2016 Dec;30(12):4289-4300. doi: 10.1096/fj.201600639R. Epub 2016 Sep 19. FASEB J. 2016. PMID: 27645259
-Zhakupova, A., Debeuf, N., Krols, M., Toussaint, W., Vanhoutte, L., Alecu, I., Kutalik, Z., Vollenweider, P., Ernst, D., von Eckardstein, A., Lambrecht, B. N., Janssens, S., Hornemann, T. ORMDL3 expression levels have no influence on the activity of serine palmitoy …
-Zhakupova, A., Debeuf, N., Krols, M., Toussaint, W., Vanhoutte, L., Alecu, I., Kutalik, Z., Vollenweider, P., Ernst, D., von Eckardstein, A …
The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice.
Debeuf N, Zhakupova A, Steiner R, Van Gassen S, Deswarte K, Fayazpour F, Van Moorleghem J, Vergote K, Pavie B, Lemeire K, Hammad H, Hornemann T, Janssens S, Lambrecht BN. Debeuf N, et al. Among authors: hornemann t. J Allergy Clin Immunol. 2019 Dec;144(6):1648-1659.e9. doi: 10.1016/j.jaci.2019.06.041. Epub 2019 Jul 20. J Allergy Clin Immunol. 2019. PMID: 31330218 Free PMC article.
Plasma 1-deoxysphingolipids are early predictors of incident type 2 diabetes mellitus.
Mwinyi J, Boström A, Fehrer I, Othman A, Waeber G, Marti-Soler H, Vollenweider P, Marques-Vidal P, Schiöth HB, von Eckardstein A, Hornemann T. Mwinyi J, et al. Among authors: hornemann t. PLoS One. 2017 May 4;12(5):e0175776. doi: 10.1371/journal.pone.0175776. eCollection 2017. PLoS One. 2017. PMID: 28472035 Free PMC article.
Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome?
Othman A, Rütti MF, Ernst D, Saely CH, Rein P, Drexel H, Porretta-Serapiglia C, Lauria G, Bianchi R, von Eckardstein A, Hornemann T. Othman A, et al. Among authors: hornemann t. Diabetologia. 2012 Feb;55(2):421-31. doi: 10.1007/s00125-011-2384-1. Epub 2011 Nov 29. Diabetologia. 2012. PMID: 22124606
146 results