Schaffer PA - Search Results

1

Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.

Coen DM, Kosz-Vnenchak M, Jacobson JG, Leib DA, Bogard CL, Schaffer PA, Tyler KL, Knipe DM. Coen DM, et al. Among authors: schaffer pa. Proc Natl Acad Sci U S A. 1989 Jun;86(12):4736-40. doi: 10.1073/pnas.86.12.4736. Proc Natl Acad Sci U S A. 1989. PMID: 2543985 Free PMC article.

2

Neither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virus.

Chen SH, Lee LY, Garber DA, Schaffer PA, Knipe DM, Coen DM. Chen SH, et al. Among authors: schaffer pa. J Virol. 2002 May;76(10):4764-72. doi: 10.1128/jvi.76.10.4764-4772.2002. J Virol. 2002. PMID: 11967293 Free PMC article.

3

The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency.

Leib DA, Nadeau KC, Rundle SA, Schaffer PA. Leib DA, et al. Among authors: schaffer pa. Proc Natl Acad Sci U S A. 1991 Jan 1;88(1):48-52. doi: 10.1073/pnas.88.1.48. Proc Natl Acad Sci U S A. 1991. PMID: 1846042 Free PMC article.

4

Specific inhibitors of herpes simplex virus thymidine kinase diminish reactivation of latent virus from explanted murine ganglia.

Leib DA, Ruffner KL, Hildebrand C, Schaffer PA, Wright GE, Coen DM. Leib DA, et al. Among authors: schaffer pa. Antimicrob Agents Chemother. 1990 Jun;34(6):1285-6. doi: 10.1128/AAC.34.6.1285. Antimicrob Agents Chemother. 1990. PMID: 2168150 Free PMC article.

5

Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.

Leib DA, Coen DM, Bogard CL, Hicks KA, Yager DR, Knipe DM, Tyler KL, Schaffer PA. Leib DA, et al. Among authors: schaffer pa. J Virol. 1989 Feb;63(2):759-68. doi: 10.1128/JVI.63.2.759-768.1989. J Virol. 1989. PMID: 2536101 Free PMC article.

6

A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency.

Leib DA, Bogard CL, Kosz-Vnenchak M, Hicks KA, Coen DM, Knipe DM, Schaffer PA. Leib DA, et al. Among authors: schaffer pa. J Virol. 1989 Jul;63(7):2893-900. doi: 10.1128/JVI.63.7.2893-2900.1989. J Virol. 1989. PMID: 2542601 Free PMC article.

7

Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1.

Coen DM, Schaffer PA. Coen DM, et al. Among authors: schaffer pa. Proc Natl Acad Sci U S A. 1980 Apr;77(4):2265-9. doi: 10.1073/pnas.77.4.2265. Proc Natl Acad Sci U S A. 1980. PMID: 6246531 Free PMC article.

8

The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency.

Cai W, Astor TL, Liptak LM, Cho C, Coen DM, Schaffer PA. Cai W, et al. Among authors: schaffer pa. J Virol. 1993 Dec;67(12):7501-12. doi: 10.1128/JVI.67.12.7501-7512.1993. J Virol. 1993. PMID: 8230470 Free PMC article.

9

A viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus.

Chen SH, Kramer MF, Schaffer PA, Coen DM. Chen SH, et al. Among authors: schaffer pa. J Virol. 1997 Aug;71(8):5878-84. doi: 10.1128/JVI.71.8.5878-5884.1997. J Virol. 1997. PMID: 9223477 Free PMC article.

10

Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation.

Chen SH, Garber DA, Schaffer PA, Knipe DM, Coen DM. Chen SH, et al. Among authors: schaffer pa. Virology. 2000 Dec 5;278(1):207-16. doi: 10.1006/viro.2000.0643. Virology. 2000. PMID: 11112495 Free article.

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