Gotoh T - Search Results

1

Discovery of novel tetrahydroisoquinoline derivatives as orally active N-type calcium channel blockers with high selectivity for hERG potassium channels.

Ogiyama T, Inoue M, Honda S, Yamada H, Watanabe T, Gotoh T, Kiso T, Koakutsu A, Kakimoto S, Shishikura J. Ogiyama T, et al. Among authors: gotoh t. Bioorg Med Chem. 2014 Dec 15;22(24):6899-907. doi: 10.1016/j.bmc.2014.10.020. Epub 2014 Oct 22. Bioorg Med Chem. 2014. PMID: 25456079

2

Discovery of a 1-isopropyltetrahydroisoquinoline derivative as an orally active N-type calcium channel blocker for neuropathic pain.

Ogiyama T, Yonezawa K, Inoue M, Watanabe T, Sugano Y, Gotoh T, Kiso T, Koakutsu A, Kakimoto S, Shishikura JI. Ogiyama T, et al. Among authors: gotoh t. Bioorg Med Chem. 2015 Aug 1;23(15):4624-4637. doi: 10.1016/j.bmc.2015.05.030. Epub 2015 May 27. Bioorg Med Chem. 2015. PMID: 26071371

3

Discovery of an 8-methoxytetrahydroisoquinoline derivative as an orally active N-type calcium channel blocker for neuropathic pain without CYP inhibition liability.

Ogiyama T, Yonezawa K, Inoue M, Katayama N, Watanabe T, Yoshimura S, Gotoh T, Kiso T, Koakutsu A, Kakimoto S, Shishikura JI. Ogiyama T, et al. Among authors: gotoh t. Bioorg Med Chem. 2015 Aug 1;23(15):4638-4648. doi: 10.1016/j.bmc.2015.05.053. Epub 2015 Jun 3. Bioorg Med Chem. 2015. PMID: 26078010

4

Spontaneous and evoked pain-associated behaviors in a rat model of neuropathic pain respond differently to drugs with different mechanisms of action.

Murai N, Sekizawa T, Gotoh T, Watabiki T, Takahashi M, Kakimoto S, Takahashi Y, Iino M, Nagakura Y. Murai N, et al. Among authors: gotoh t. Pharmacol Biochem Behav. 2016 Feb;141:10-7. doi: 10.1016/j.pbb.2015.11.008. Epub 2015 Nov 17. Pharmacol Biochem Behav. 2016. PMID: 26597514

5

Comparison Between Attenuation Measurement and the Controlled Attenuation Parameter for the Assessment of Hepatic Steatosis Based on MRI Images.

Gotoh T, Kumada T, Ogawa S, Niwa F, Toyoda H, Hirooka M, Koizumi Y, Hiasa Y, Akita T, Tanaka J, Shimizu M. Gotoh T, et al. Liver Int. 2025 Jan;45(1):e16210. doi: 10.1111/liv.16210. Liver Int. 2025. PMID: 39673700

6

The six-spotted spider mite, Eotetranychus sexmaculatus (Riley) (Trombidiformes: Tetranychidae) in Australia, New Zealand, Japan and USA: a revised morphological and molecular-based concept, synonyms, and related species.

Beard JJ, Beaulieu F, Knee W, Gotoh T. Beard JJ, et al. Among authors: gotoh t. Zootaxa. 2024 Apr 2;5432(3):349-378. doi: 10.11646/zootaxa.5432.3.2. Zootaxa. 2024. PMID: 39645780

7

Draft genome sequence of Aurantiochytrium spp. strains L3W, 9LR, 8W, 10W, and 10LW, a fatty acid-producing thraustochytrids from food wastes.

Suenaga T, Mitarai Y, Anh TN, Gotoh T, Nishijima W, Nakai S. Suenaga T, et al. Among authors: gotoh t. Microbiol Resour Announc. 2024 Dec 12;13(12):e0065324. doi: 10.1128/mra.00653-24. Epub 2024 Nov 13. Microbiol Resour Announc. 2024. PMID: 39535196 Free PMC article.

8

Physician attending cardiac magnetic resonance imaging for early aortic structural valve deterioration: non-invasive method to identify the regurgitate location.

Kuroda T, Yamada M, Imaoka T, Gotoh T, Takagi K. Kuroda T, et al. Among authors: gotoh t. Cardiovasc Interv Ther. 2024 Nov 7. doi: 10.1007/s12928-024-01048-8. Online ahead of print. Cardiovasc Interv Ther. 2024. PMID: 39508950 No abstract available.

9

Heavy water inhibits DNA double-strand break repairs and disturbs cellular transcription, presumably via quantum-level mechanisms of kinetic isotope effects on hydrolytic enzyme reactions.

Yasuda T, Nakajima N, Ogi T, Yanaka T, Tanaka I, Gotoh T, Kagawa W, Sugasawa K, Tajima K. Yasuda T, et al. Among authors: gotoh t. PLoS One. 2024 Oct 3;19(10):e0309689. doi: 10.1371/journal.pone.0309689. eCollection 2024. PLoS One. 2024. PMID: 39361575 Free PMC article.

10

Maternal Undernutrition Affects Fetal Thymus DNA Methylation, Gene Expression, and, Thereby, Metabolism and Immunopoiesis in Wagyu (Japanese Black) Cattle.

Phomvisith O, Muroya S, Otomaru K, Oshima K, Oshima I, Nishino D, Haginouchi T, Gotoh T. Phomvisith O, et al. Among authors: gotoh t. Int J Mol Sci. 2024 Aug 26;25(17):9242. doi: 10.3390/ijms25179242. Int J Mol Sci. 2024. PMID: 39273192 Free PMC article.

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