Siksnys V - Search Results

1

Programmable RNA shredding by the type III-A CRISPR-Cas system of Streptococcus thermophilus.

Tamulaitis G, Kazlauskiene M, Manakova E, Venclovas Č, Nwokeoji AO, Dickman MJ, Horvath P, Siksnys V. Tamulaitis G, et al. Among authors: siksnys v. Mol Cell. 2014 Nov 20;56(4):506-17. doi: 10.1016/j.molcel.2014.09.027. Epub 2014 Nov 6. Mol Cell. 2014. PMID: 25458845 Free article.

2

Different enzymes with similar structures involved in Mg(2+)-mediated polynucleotidyl transfer.

Venclovas C, Siksnys V. Venclovas C, et al. Among authors: siksnys v. Nat Struct Biol. 1995 Oct;2(10):838-41. doi: 10.1038/nsb1095-838. Nat Struct Biol. 1995. PMID: 7552704

3

Five-stranded beta-sheet sandwiched with two alpha-helices: a structural link between restriction endonucleases EcoRI and EcoRV.

Venclovas C, Timinskas A, Siksnys V. Venclovas C, et al. Among authors: siksnys v. Proteins. 1994 Nov;20(3):279-82. doi: 10.1002/prot.340200308. Proteins. 1994. PMID: 7892176

4

Alternative arrangements of catalytic residues at the active sites of restriction enzymes.

Tamulaitis G, Solonin AS, Siksnys V. Tamulaitis G, et al. Among authors: siksnys v. FEBS Lett. 2002 May 8;518(1-3):17-22. doi: 10.1016/s0014-5793(02)02621-2. FEBS Lett. 2002. PMID: 11997010 Free article.

5

Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease.

Grazulis S, Manakova E, Roessle M, Bochtler M, Tamulaitiene G, Huber R, Siksnys V. Grazulis S, et al. Among authors: siksnys v. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15797-802. doi: 10.1073/pnas.0507949102. Epub 2005 Oct 24. Proc Natl Acad Sci U S A. 2005. PMID: 16247004 Free PMC article.

6

Biochemical and mutational analysis of EcoRII functional domains reveals evolutionary links between restriction enzymes.

Tamulaitis G, Mucke M, Siksnys V. Tamulaitis G, et al. Among authors: siksnys v. FEBS Lett. 2006 Mar 6;580(6):1665-71. doi: 10.1016/j.febslet.2006.02.010. Epub 2006 Feb 17. FEBS Lett. 2006. PMID: 16497303 Free article.

7

Simultaneous binding of three recognition sites is necessary for a concerted plasmid DNA cleavage by EcoRII restriction endonuclease.

Tamulaitis G, Sasnauskas G, Mucke M, Siksnys V. Tamulaitis G, et al. Among authors: siksnys v. J Mol Biol. 2006 Apr 28;358(2):406-19. doi: 10.1016/j.jmb.2006.02.024. Epub 2006 Feb 28. J Mol Biol. 2006. PMID: 16529772

8

Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease.

Bochtler M, Szczepanowski RH, Tamulaitis G, Grazulis S, Czapinska H, Manakova E, Siksnys V. Bochtler M, et al. Among authors: siksnys v. EMBO J. 2006 May 17;25(10):2219-29. doi: 10.1038/sj.emboj.7601096. Epub 2006 Apr 20. EMBO J. 2006. PMID: 16628220 Free PMC article.

9

Restriction endonuclease BpuJI specific for the 5'-CCCGT sequence is related to the archaeal Holliday junction resolvase family.

Sukackaite R, Lagunavicius A, Stankevicius K, Urbanke C, Venclovas C, Siksnys V. Sukackaite R, et al. Among authors: siksnys v. Nucleic Acids Res. 2007;35(7):2377-89. doi: 10.1093/nar/gkm164. Epub 2007 Mar 28. Nucleic Acids Res. 2007. PMID: 17392342 Free PMC article.

10

Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.

Sokolowska M, Kaus-Drobek M, Czapinska H, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M. Sokolowska M, et al. Among authors: siksnys v. J Mol Biol. 2007 Jun 8;369(3):722-34. doi: 10.1016/j.jmb.2007.03.018. Epub 2007 Mar 15. J Mol Biol. 2007. PMID: 17445830

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