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Page 1
Continuous T cell receptor signals maintain a functional regulatory T cell pool.
Vahl JC, Drees C, Heger K, Heink S, Fischer JC, Nedjic J, Ohkura N, Morikawa H, Poeck H, Schallenberg S, Rieß D, Hein MY, Buch T, Polic B, Schönle A, Zeiser R, Schmitt-Gräff A, Kretschmer K, Klein L, Korn T, Sakaguchi S, Schmidt-Supprian M. Vahl JC, et al. Immunity. 2014 Nov 20;41(5):722-36. doi: 10.1016/j.immuni.2014.10.012. Epub 2014 Nov 6. Immunity. 2014. PMID: 25464853 Free article.
TCR signals fuel Treg cells.
Drees C, Vahl JC, Schmidt-Supprian M. Drees C, et al. Among authors: vahl jc. Oncotarget. 2015 Sep 8;6(26):21773-4. doi: 10.18632/oncotarget.4881. Oncotarget. 2015. PMID: 26318042 Free PMC article. No abstract available.
Roquin Paralogs Differentially Regulate Functional NKT Cell Subsets.
Drees C, Vahl JC, Bortoluzzi S, Heger KD, Fischer JC, Wunderlich FT, Peschel C, Schmidt-Supprian M. Drees C, et al. Among authors: vahl jc. J Immunol. 2017 Apr 1;198(7):2747-2759. doi: 10.4049/jimmunol.1601732. Epub 2017 Feb 10. J Immunol. 2017. PMID: 28188245
B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice.
Chu Y, Vahl JC, Kumar D, Heger K, Bertossi A, Wójtowicz E, Soberon V, Schenten D, Mack B, Reutelshöfer M, Beyaert R, Amann K, van Loo G, Schmidt-Supprian M. Chu Y, et al. Among authors: vahl jc. Blood. 2011 Feb 17;117(7):2227-36. doi: 10.1182/blood-2010-09-306019. Epub 2010 Nov 18. Blood. 2011. PMID: 21088135 Free article.
A20-deficient mast cells exacerbate inflammatory responses in vivo.
Heger K, Fierens K, Vahl JC, Aszodi A, Peschke K, Schenten D, Hammad H, Beyaert R, Saur D, van Loo G, Roers A, Lambrecht BN, Kool M, Schmidt-Supprian M. Heger K, et al. Among authors: vahl jc. PLoS Biol. 2014 Jan;12(1):e1001762. doi: 10.1371/journal.pbio.1001762. Epub 2014 Jan 14. PLoS Biol. 2014. PMID: 24453940 Free PMC article.