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Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus.
Pidot SJ, Klatt S, Ates LS, Frigui W, Sayes F, Majlessi L, Izumi H, Monk IR, Porter JL, Bennett-Wood V, Seemann T, Otter A, Taiaroa G, Cook GM, West N, Tobias NJ, Fuerst JA, Stutz MD, Pellegrini M, McConville M, Brosch R, Stinear TP. Pidot SJ, et al. Among authors: mcconville m. PLoS Pathog. 2024 Aug 29;20(8):e1012440. doi: 10.1371/journal.ppat.1012440. eCollection 2024 Aug. PLoS Pathog. 2024. PMID: 39207937 Free PMC article.
Hit-to-lead optimization of 2-aminoquinazolines as anti-microbial agents against Leishmania donovani.
Das N, Roy J, Patra B, Saunders E, Sarkar D, Goon S, Sinha BP, Roy S, Roy S, Sarif J, Bandopadhyay P, Barik S, Mukherjee S, McNamara N, Varghese S, Simpson K, Baell J, McConville M, Ganguly D, Talukdar A. Das N, et al. Among authors: mcconville m. Eur J Med Chem. 2024 Apr 5;269:116256. doi: 10.1016/j.ejmech.2024.116256. Epub 2024 Feb 27. Eur J Med Chem. 2024. PMID: 38461679
Structure-activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling.
Ahmed AA, Chen S, Roman-Escorza M, Angell R, Oxenford S, McConville M, Barton N, Sunose M, Neidle D, Haider S, Arshad T, Neidle S. Ahmed AA, et al. Among authors: mcconville m. Sci Rep. 2024 Feb 11;14(1):3447. doi: 10.1038/s41598-024-54080-2. Sci Rep. 2024. PMID: 38342953 Free PMC article.
PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum.
Jonsdottir TK, Elsworth B, Cobbold S, Gabriela M, Ploeger E, Parkyn Schneider M, Charnaud SC, Dans MG, McConville M, Bullen HE, Crabb BS, Gilson PR. Jonsdottir TK, et al. Among authors: mcconville m. PLoS Pathog. 2023 Jul 31;19(7):e1011006. doi: 10.1371/journal.ppat.1011006. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37523385 Free PMC article.
353 results