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New 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides inhibit hepatitis C virus replication via suppression of cyclooxygenase-2.
Manvar D, Pelliccia S, La Regina G, Famiglini V, Coluccia A, Ruggieri A, Anticoli S, Lee JC, Basu A, Cevik O, Nencioni L, Palamara AT, Zamperini C, Botta M, Neyts J, Leyssen P, Kaushik-Basu N, Silvestri R. Manvar D, et al. Among authors: basu a. Eur J Med Chem. 2015 Jan 27;90:497-506. doi: 10.1016/j.ejmech.2014.11.042. Epub 2014 Nov 27. Eur J Med Chem. 2015. PMID: 25483263 Free article.
Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives.
Nichols DB, Fournet G, Gurukumar KR, Basu A, Lee JC, Sakamoto N, Kozielski F, Musmuca I, Joseph B, Ragno R, Kaushik-Basu N. Nichols DB, et al. Among authors: basu a. Eur J Med Chem. 2012 Mar;49:191-9. doi: 10.1016/j.ejmech.2012.01.010. Epub 2012 Jan 12. Eur J Med Chem. 2012. PMID: 22280819 Free PMC article.
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.
Manfroni G, Cannalire R, Barreca ML, Kaushik-Basu N, Leyssen P, Winquist J, Iraci N, Manvar D, Paeshuyse J, Guhamazumder R, Basu A, Sabatini S, Tabarrini O, Danielson UH, Neyts J, Cecchetti V. Manfroni G, et al. Among authors: basu a. J Med Chem. 2014 Mar 13;57(5):1952-63. doi: 10.1021/jm401362f. Epub 2013 Nov 6. J Med Chem. 2014. PMID: 24131104 Free PMC article.
New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors.
Manfroni G, Manvar D, Barreca ML, Kaushik-Basu N, Leyssen P, Paeshuyse J, Cannalire R, Iraci N, Basu A, Chudaev M, Zamperini C, Dreassi E, Sabatini S, Tabarrini O, Neyts J, Cecchetti V. Manfroni G, et al. Among authors: basu a. J Med Chem. 2014 Apr 24;57(8):3247-62. doi: 10.1021/jm401688h. Epub 2014 Apr 2. J Med Chem. 2014. PMID: 24654886 Free PMC article.
5-Carba-pterocarpens: A new scaffold with anti-HCV activity.
Fernandes TA, Manvar D, Domingos JLO, Basu A, Nichols DB, Kaushik-Basu N, Costa PRR. Fernandes TA, et al. Among authors: basu a. Eur J Med Chem. 2016 Apr 13;112:33-38. doi: 10.1016/j.ejmech.2016.02.010. Epub 2016 Feb 6. Eur J Med Chem. 2016. PMID: 26874742
Bicyclic octahydrocyclohepta[b]pyrrol-4(1H)one derivatives as novel selective anti-hepatitis C virus agents.
Kaushik-Basu N, Ratmanova NK, Manvar D, Belov DS, Cevik O, Basu A, Yerukhimovich MM, Lukyanenko ER, Andreev IA, Belov GM, Manfroni G, Cecchetti V, Frick DN, Kurkin AV, Altieri A, Barreca ML. Kaushik-Basu N, et al. Among authors: basu a. Eur J Med Chem. 2016 Oct 21;122:319-325. doi: 10.1016/j.ejmech.2016.06.041. Epub 2016 Jun 23. Eur J Med Chem. 2016. PMID: 27376494
3,111 results