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Page 1
B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.
Qian J, Wang Q, Dose M, Pruett N, Kieffer-Kwon KR, Resch W, Liang G, Tang Z, Mathé E, Benner C, Dubois W, Nelson S, Vian L, Oliveira TY, Jankovic M, Hakim O, Gazumyan A, Pavri R, Awasthi P, Song B, Liu G, Chen L, Zhu S, Feigenbaum L, Staudt L, Murre C, Ruan Y, Robbiani DF, Pan-Hammarström Q, Nussenzweig MC, Casellas R. Qian J, et al. Cell. 2014 Dec 18;159(7):1524-37. doi: 10.1016/j.cell.2014.11.013. Epub 2014 Dec 4. Cell. 2014. PMID: 25483777 Free PMC article.
Global regulation of promoter melting in naive lymphocytes.
Kouzine F, Wojtowicz D, Yamane A, Resch W, Kieffer-Kwon KR, Bandle R, Nelson S, Nakahashi H, Awasthi P, Feigenbaum L, Menoni H, Hoeijmakers J, Vermeulen W, Ge H, Przytycka TM, Levens D, Casellas R. Kouzine F, et al. Cell. 2013 May 23;153(5):988-99. doi: 10.1016/j.cell.2013.04.033. Cell. 2013. PMID: 23706737 Free PMC article.
Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.
Kieffer-Kwon KR, Tang Z, Mathe E, Qian J, Sung MH, Li G, Resch W, Baek S, Pruett N, Grøntved L, Vian L, Nelson S, Zare H, Hakim O, Reyon D, Yamane A, Nakahashi H, Kovalchuk AL, Zou J, Joung JK, Sartorelli V, Wei CL, Ruan X, Hager GL, Ruan Y, Casellas R. Kieffer-Kwon KR, et al. Cell. 2013 Dec 19;155(7):1507-20. doi: 10.1016/j.cell.2013.11.039. Cell. 2013. PMID: 24360274 Free PMC article.
The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination.
Delgado-Benito V, Rosen DB, Wang Q, Gazumyan A, Pai JA, Oliveira TY, Sundaravinayagam D, Zhang W, Andreani M, Keller L, Kieffer-Kwon KR, Pękowska A, Jung S, Driesner M, Subbotin RI, Casellas R, Chait BT, Nussenzweig MC, Di Virgilio M. Delgado-Benito V, et al. Among authors: kieffer kwon kr. Mol Cell. 2018 Nov 15;72(4):636-649.e8. doi: 10.1016/j.molcel.2018.08.042. Epub 2018 Oct 4. Mol Cell. 2018. PMID: 30293785 Free PMC article.
DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.
Hakim O, Resch W, Yamane A, Klein I, Kieffer-Kwon KR, Jankovic M, Oliveira T, Bothmer A, Voss TC, Ansarah-Sobrinho C, Mathe E, Liang G, Cobell J, Nakahashi H, Robbiani DF, Nussenzweig A, Hager GL, Nussenzweig MC, Casellas R. Hakim O, et al. Nature. 2012 Feb 7;484(7392):69-74. doi: 10.1038/nature10909. Nature. 2012. PMID: 22314321 Free PMC article.
A genome-wide map of CTCF multivalency redefines the CTCF code.
Nakahashi H, Kieffer Kwon KR, Resch W, Vian L, Dose M, Stavreva D, Hakim O, Pruett N, Nelson S, Yamane A, Qian J, Dubois W, Welsh S, Phair RD, Pugh BF, Lobanenkov V, Hager GL, Casellas R. Nakahashi H, et al. Cell Rep. 2013 May 30;3(5):1678-1689. doi: 10.1016/j.celrep.2013.04.024. Epub 2013 May 23. Cell Rep. 2013. PMID: 23707059 Free PMC article.
RAG Represents a Widespread Threat to the Lymphocyte Genome.
Teng G, Maman Y, Resch W, Kim M, Yamane A, Qian J, Kieffer-Kwon KR, Mandal M, Ji Y, Meffre E, Clark MR, Cowell LG, Casellas R, Schatz DG. Teng G, et al. Cell. 2015 Aug 13;162(4):751-65. doi: 10.1016/j.cell.2015.07.009. Epub 2015 Jul 30. Cell. 2015. PMID: 26234156 Free PMC article.
21 results