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Development of a duplex real-time RT-qPCR assay to monitor genome replication, gene expression and gene insert stability during in vivo replication of a prototype live attenuated canine distemper virus vector encoding SIV gag.
Coleman JW, Wright KJ, Wallace OL, Sharma P, Arendt H, Martinez J, DeStefano J, Zamb TP, Zhang X, Parks CL. Coleman JW, et al. Among authors: wallace ol. J Virol Methods. 2015 Mar;213:26-37. doi: 10.1016/j.jviromet.2014.11.015. Epub 2014 Dec 5. J Virol Methods. 2015. PMID: 25486083 Free PMC article.
Membrane-bound SIV envelope trimers are immunogenic in ferrets after intranasal vaccination with a replication-competent canine distemper virus vector.
Zhang X, Wallace O, Wright KJ, Backer M, Coleman JW, Koehnke R, Frenk E, Domi A, Chiuchiolo MJ, DeStefano J, Narpala S, Powell R, Morrow G, Boggiano C, Zamb TJ, Richter King C, Parks CL. Zhang X, et al. Virology. 2013 Nov;446(1-2):25-36. doi: 10.1016/j.virol.2013.07.012. Epub 2013 Aug 9. Virology. 2013. PMID: 24074564 Free article.
Canine distemper virus neutralization activity is low in human serum and it is sensitive to an amino acid substitution in the hemagglutinin protein.
Zhang X, Wallace OL, Domi A, Wright KJ, Driscoll J, Anzala O, Sanders EJ, Kamali A, Karita E, Allen S, Fast P, Gilmour J, Price MA, Parks CL. Zhang X, et al. Among authors: wallace ol. Virology. 2015 Aug;482:218-24. doi: 10.1016/j.virol.2015.03.035. Epub 2015 Apr 14. Virology. 2015. PMID: 25880113 Free PMC article.