Bayliss M - Search Results

1

The Use of Long-term Hepatocyte Cultures for Detecting Induction of Drug Metabolising Enzymes: The Current Status.

Coecke S, Rogiers V, Bayliss M, Castell J, Doehmer J, Fabre G, Fry J, Kern A, Westmoreland C. Coecke S, et al. Among authors: bayliss m. Altern Lab Anim. 1999 Jul-Aug;27(4):579-638. doi: 10.1177/026119299902700408. Altern Lab Anim. 1999. PMID: 25487865

2

Pharmacokinetics in Early Drug Research.

Leahy DE, Duncan R, Ahr HJ, Bayliss MK, de Boer AB, Darvas F, Fentem JH, Fry JR, Hopkins R, Houston JB, Karlsson J, Kedderis GL, Pratten MK, Prieto P, Smith DA, Straughan DW. Leahy DE, et al. Among authors: bayliss mk. Altern Lab Anim. 1997 Jan-Feb;25(1):17-31. Altern Lab Anim. 1997. PMID: 26554347 No abstract available.

3

A commentary on the use of hepatocytes in drug metabolism studies during drug discovery and development.

Cross DM, Bayliss MK. Cross DM, et al. Among authors: bayliss mk. Drug Metab Rev. 2000 May;32(2):219-40. doi: 10.1081/dmr-100100574. Drug Metab Rev. 2000. PMID: 10774777 Review.

4

Drug metabolism assays and their use in drug discovery.

Bayliss MK, Eddershaw PJ. Bayliss MK, et al. Ernst Schering Res Found Workshop. 2002;(37):69-79. doi: 10.1007/978-3-662-04383-7_4. Ernst Schering Res Found Workshop. 2002. PMID: 11975201 Review. No abstract available.

5

Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans.

Carlile DJ, Hakooz N, Bayliss MK, Houston JB. Carlile DJ, et al. Among authors: bayliss mk. Br J Clin Pharmacol. 1999 Jun;47(6):625-35. doi: 10.1046/j.1365-2125.1999.00935.x. Br J Clin Pharmacol. 1999. PMID: 10383540 Free PMC article.

6

The metabolism of the 5HT3 antagonists, ondansetron, alosetron and GR87442 II: investigation into the in vitro methods used to predict the in vivo hepatic clearance of ondansetron, alosetron and GR87442 in the rat, dog and human.

Somers GI, Bayliss MK, Houston JB. Somers GI, et al. Among authors: bayliss mk. Xenobiotica. 2007 Aug;37(8):855-69. doi: 10.1080/00498250701474058. Xenobiotica. 2007. PMID: 17701833

7

The metabolism of the 5HT3 antagonists ondansetron, alosetron and GR87442 I: a comparison of in vitro and in vivo metabolism and in vitro enzyme kinetics in rat, dog and human hepatocytes, microsomes and recombinant human enzymes.

Somers GI, Harris AJ, Bayliss MK, Houston JB. Somers GI, et al. Among authors: bayliss mk. Xenobiotica. 2007 Aug;37(8):832-54. doi: 10.1080/00498250701485575. Xenobiotica. 2007. PMID: 17701832

8

Utility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and man.

Bayliss MK, Bell JA, Jenner WN, Park GR, Wilson K. Bayliss MK, et al. Xenobiotica. 1999 Mar;29(3):253-68. doi: 10.1080/004982599238650. Xenobiotica. 1999. PMID: 10219966

9

Prediction of intrinsic clearance of loxtidine from kinetic studies in rat, dog and human hepatocytes.

Bayliss MK, Bell JA, Jenner WN, Wilson K. Bayliss MK, et al. Biochem Soc Trans. 1990 Dec;18(6):1198-9. doi: 10.1042/bst0181198. Biochem Soc Trans. 1990. PMID: 1982435 No abstract available.

10

Applications of molecular biology and in vitro technology to drug metabolism studies: an industrial perspective.

Tarbit MH, Bayliss MK, Herriott D, Hood SR, Hutson JL, Park GR, Serabjit-Singh CJ. Tarbit MH, et al. Among authors: bayliss mk. Biochem Soc Trans. 1993 Nov;21(4):1018-23. doi: 10.1042/bst0211018. Biochem Soc Trans. 1993. PMID: 8131890 Review. No abstract available.

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