ERK1/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans.
Subramaniam S, Ozdener MH, Abdoul-Azize S, Saito K, Malik B, Maquart G, Hashimoto T, Marambaud P, Aribi M, Tordoff MG, Besnard P, Khan NA.
Subramaniam S, et al.
FASEB J. 2016 Oct;30(10):3489-3500. doi: 10.1096/fj.201600422R. Epub 2016 Jun 29.
FASEB J. 2016.
PMID: 27358389
Free PMC article.
Our data demonstrate that ERK1/2-MAPK cascade is regulated by the opening of CALHM1 Ca(2+) channel in TBCs to modulate orogustatory detection of dietary lipids in mice and humans.-Subramaniam, S., Ozdener, M. H., Abdoul-Azize, S., Saito, K., Malik, B., Maquar …
Our data demonstrate that ERK1/2-MAPK cascade is regulated by the opening of CALHM1 Ca(2+) channel in TBCs to modulate orogustatory detectio …