Rosen A - Search Results

1

Dynamic conformations of nucleophosmin (NPM1) at a key monomer-monomer interface affect oligomer stability and interactions with granzyme B.

Duan-Porter WD, Woods VL Jr, Maurer KD, Li S, Rosen A. Duan-Porter WD, et al. Among authors: rosen a. PLoS One. 2014 Dec 9;9(12):e115062. doi: 10.1371/journal.pone.0115062. eCollection 2014. PLoS One. 2014. PMID: 25490769 Free PMC article.

2

Unique conformation of cancer autoantigen B23 in hepatoma: a mechanism for specificity in the autoimmune response.

Ulanet DB, Torbenson M, Dang CV, Casciola-Rosen L, Rosen A. Ulanet DB, et al. Among authors: rosen a. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12361-6. doi: 10.1073/pnas.2035245100. Epub 2003 Sep 30. Proc Natl Acad Sci U S A. 2003. PMID: 14519847 Free PMC article.

3

Autoantigens: the critical partner in initiating and propagating systemic autoimmunity.

Duan-Porter WD, Casciola-Rosen L, Rosen A. Duan-Porter WD, et al. Among authors: rosen a. Ann N Y Acad Sci. 2005 Dec;1062:127-36. doi: 10.1196/annals.1358.015. Ann N Y Acad Sci. 2005. PMID: 16461795 Review.

4

Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis.

Andrade F, Roy S, Nicholson D, Thornberry N, Rosen A, Casciola-Rosen L. Andrade F, et al. Among authors: rosen a. Immunity. 1998 Apr;8(4):451-60. doi: 10.1016/s1074-7613(00)80550-6. Immunity. 1998. PMID: 9586635 Free article.

5

The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis.

Mahoney JA, Odin JA, White SM, Shaffer D, Koff A, Casciola-Rosen L, Rosen A. Mahoney JA, et al. Among authors: rosen a. Biochem J. 2002 Feb 1;361(Pt 3):587-95. doi: 10.1042/0264-6021:3610587. Biochem J. 2002. PMID: 11802788 Free PMC article.

6

Selective cleavage of nucleolar autoantigen B23 by granzyme B in differentiated vascular smooth muscle cells: insights into the association of specific autoantibodies with distinct disease phenotypes.

Ulanet DB, Flavahan NA, Casciola-Rosen L, Rosen A. Ulanet DB, et al. Among authors: rosen a. Arthritis Rheum. 2004 Jan;50(1):233-41. doi: 10.1002/art.11485. Arthritis Rheum. 2004. PMID: 14730621 Free article.

7

The MPAC domain is a novel mitotically regulated domain, removed by apoptotic protease cleavage during cell death.

Spinette S, Mahoney JA, Rosen A. Spinette S, et al. Among authors: rosen a. Biochem Biophys Res Commun. 2006 Sep 8;347(4):1103-12. doi: 10.1016/j.bbrc.2006.06.194. Epub 2006 Jul 14. Biochem Biophys Res Commun. 2006. PMID: 16870146

8

Granzyme B cleavage of autoantigens in autoimmunity.

Darrah E, Rosen A. Darrah E, et al. Among authors: rosen a. Cell Death Differ. 2010 Apr;17(4):624-32. doi: 10.1038/cdd.2009.197. Epub 2010 Jan 15. Cell Death Differ. 2010. PMID: 20075942 Free PMC article. Review.

9

A novel conserved isoform of the ubiquitin ligase UFD2a/UBE4B is expressed exclusively in mature striated muscle cells.

Mammen AL, Mahoney JA, St Germain A, Badders N, Taylor JP, Rosen A, Spinette S. Mammen AL, et al. Among authors: rosen a. PLoS One. 2011;6(12):e28861. doi: 10.1371/journal.pone.0028861. Epub 2011 Dec 9. PLoS One. 2011. PMID: 22174917 Free PMC article.

10

Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis.

Darrah E, Kim A, Zhang X, Boronina T, Cole RN, Fava A, Giles JT, Bingham III CO, Chalmers MJ, Griffin PR, Sadegh-Nasseri S, Rosen A. Darrah E, et al. Among authors: rosen a. J Proteome Res. 2017 Jan 6;16(1):355-365. doi: 10.1021/acs.jproteome.6b00617. Epub 2016 Oct 20. J Proteome Res. 2017. PMID: 27700100 Free PMC article.

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