Orkin SH - Search Results

1

Characterizing heterogeneity in leukemic cells using single-cell gene expression analysis.

Saadatpour A, Guo G, Orkin SH, Yuan GC. Saadatpour A, et al. Among authors: orkin sh. Genome Biol. 2014 Dec 3;15(12):525. doi: 10.1186/s13059-014-0525-9. Genome Biol. 2014. PMID: 25517911 Free PMC article.

2

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.

Shen X, Liu Y, Hsu YJ, Fujiwara Y, Kim J, Mao X, Yuan GC, Orkin SH. Shen X, et al. Among authors: orkin sh. Mol Cell. 2008 Nov 21;32(4):491-502. doi: 10.1016/j.molcel.2008.10.016. Mol Cell. 2008. PMID: 19026780 Free PMC article.

3

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.

Shen X, Kim W, Fujiwara Y, Simon MD, Liu Y, Mysliwiec MR, Yuan GC, Lee Y, Orkin SH. Shen X, et al. Among authors: orkin sh. Cell. 2009 Dec 24;139(7):1303-14. doi: 10.1016/j.cell.2009.12.003. Cell. 2009. PMID: 20064376 Free PMC article.

4

Differential roles of Sall4 isoforms in embryonic stem cell pluripotency.

Rao S, Zhen S, Roumiantsev S, McDonald LT, Yuan GC, Orkin SH. Rao S, et al. Among authors: orkin sh. Mol Cell Biol. 2010 Nov;30(22):5364-80. doi: 10.1128/MCB.00419-10. Epub 2010 Sep 13. Mol Cell Biol. 2010. PMID: 20837710 Free PMC article.

5

MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets.

Shao Z, Zhang Y, Yuan GC, Orkin SH, Waxman DJ. Shao Z, et al. Among authors: orkin sh. Genome Biol. 2012 Mar 16;13(3):R16. doi: 10.1186/gb-2012-13-3-r16. Genome Biol. 2012. PMID: 22424423 Free PMC article.

6

Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis.

Xu J, Shao Z, Glass K, Bauer DE, Pinello L, Van Handel B, Hou S, Stamatoyannopoulos JA, Mikkola HK, Yuan GC, Orkin SH. Xu J, et al. Among authors: orkin sh. Dev Cell. 2012 Oct 16;23(4):796-811. doi: 10.1016/j.devcel.2012.09.003. Epub 2012 Oct 4. Dev Cell. 2012. PMID: 23041383 Free PMC article.

7

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells.

Maclean GA, Menne TF, Guo G, Sanchez DJ, Park IH, Daley GQ, Orkin SH. Maclean GA, et al. Among authors: orkin sh. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17567-72. doi: 10.1073/pnas.1215468109. Epub 2012 Oct 8. Proc Natl Acad Sci U S A. 2012. PMID: 23045682 Free PMC article.

8

ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.

Baena E, Shao Z, Linn DE, Glass K, Hamblen MJ, Fujiwara Y, Kim J, Nguyen M, Zhang X, Godinho FJ, Bronson RT, Mucci LA, Loda M, Yuan GC, Orkin SH, Li Z. Baena E, et al. Among authors: orkin sh. Genes Dev. 2013 Mar 15;27(6):683-98. doi: 10.1101/gad.211011.112. Genes Dev. 2013. PMID: 23512661 Free PMC article.

9

Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation.

Kerenyi MA, Shao Z, Hsu YJ, Guo G, Luc S, O'Brien K, Fujiwara Y, Peng C, Nguyen M, Orkin SH. Kerenyi MA, et al. Among authors: orkin sh. Elife. 2013 Jun 18;2:e00633. doi: 10.7554/eLife.00633. Elife. 2013. PMID: 23795291 Free PMC article.

10

Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer.

Kim W, Bird GH, Neff T, Guo G, Kerenyi MA, Walensky LD, Orkin SH. Kim W, et al. Among authors: orkin sh. Nat Chem Biol. 2013 Oct;9(10):643-50. doi: 10.1038/nchembio.1331. Epub 2013 Aug 25. Nat Chem Biol. 2013. PMID: 23974116 Free PMC article.

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