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Cystamine/cysteamine rescues the dopaminergic system and shows neurorestorative properties in an animal model of Parkinson's disease.
Cisbani G, Drouin-Ouellet J, Gibrat C, Saint-Pierre M, Lagacé M, Badrinarayanan S, Lavallée-Bourget MH, Charest J, Chabrat A, Boivin L, Lebel M, Bousquet M, Lévesque M, Cicchetti F. Cisbani G, et al. Neurobiol Dis. 2015 Oct;82:430-444. doi: 10.1016/j.nbd.2015.07.012. Epub 2015 Jul 29. Neurobiol Dis. 2015. PMID: 26232588
Mutant huntingtin is present in neuronal grafts in Huntington disease patients.
Cicchetti F, Lacroix S, Cisbani G, Vallières N, Saint-Pierre M, St-Amour I, Tolouei R, Skepper JN, Hauser RA, Mantovani D, Barker RA, Freeman TB. Cicchetti F, et al. Among authors: cisbani g. Ann Neurol. 2014 Jul;76(1):31-42. doi: 10.1002/ana.24174. Epub 2014 Jun 6. Ann Neurol. 2014. PMID: 24798518
Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology.
Drouin-Ouellet J, Sawiak SJ, Cisbani G, Lagacé M, Kuan WL, Saint-Pierre M, Dury RJ, Alata W, St-Amour I, Mason SL, Calon F, Lacroix S, Gowland PA, Francis ST, Barker RA, Cicchetti F. Drouin-Ouellet J, et al. Among authors: cisbani g. Ann Neurol. 2015 Aug;78(2):160-77. doi: 10.1002/ana.24406. Epub 2015 Apr 9. Ann Neurol. 2015. PMID: 25866151
Is Huntington's disease a tauopathy?
Gratuze M, Cisbani G, Cicchetti F, Planel E. Gratuze M, et al. Among authors: cisbani g. Brain. 2016 Apr;139(Pt 4):1014-25. doi: 10.1093/brain/aww021. Epub 2016 Mar 11. Brain. 2016. PMID: 26969684 Review.
44 results