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Perforin gene transfer into hematopoietic stem cells improves immune dysregulation in murine models of perforin deficiency.
Carmo M, Risma KA, Arumugam P, Tiwari S, Hontz AE, Montiel-Equihua CA, Alonso-Ferrero ME, Blundell MP, Schambach A, Baum C, Malik P, Thrasher AJ, Jordan MB, Gaspar HB. Carmo M, et al. Among authors: jordan mb. Mol Ther. 2015 Apr;23(4):737-45. doi: 10.1038/mt.2014.242. Epub 2014 Dec 19. Mol Ther. 2015. PMID: 25523759 Free PMC article.
Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation.
Marsh RA, Vaughn G, Kim MO, Li D, Jodele S, Joshi S, Mehta PA, Davies SM, Jordan MB, Bleesing JJ, Filipovich AH. Marsh RA, et al. Among authors: jordan mb. Blood. 2010 Dec 23;116(26):5824-31. doi: 10.1182/blood-2010-04-282392. Epub 2010 Sep 20. Blood. 2010. PMID: 20855862 Free article.
Perforin is a critical physiologic regulator of T-cell activation.
Lykens JE, Terrell CE, Zoller EE, Risma K, Jordan MB. Lykens JE, et al. Among authors: jordan mb. Blood. 2011 Jul 21;118(3):618-26. doi: 10.1182/blood-2010-12-324533. Epub 2011 May 23. Blood. 2011. PMID: 21606480 Free PMC article.
151 results