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410 results

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Phase II study of monthly pasireotide LAR (SOM230C) for recurrent or progressive meningioma.
Norden AD, Ligon KL, Hammond SN, Muzikansky A, Reardon DA, Kaley TJ, Batchelor TT, Plotkin SR, Raizer JJ, Wong ET, Drappatz J, Lesser GJ, Haidar S, Beroukhim R, Lee EQ, Doherty L, Lafrankie D, Gaffey SC, Gerard M, Smith KH, McCluskey C, Phuphanich S, Wen PY. Norden AD, et al. Among authors: beroukhim r. Neurology. 2015 Jan 20;84(3):280-6. doi: 10.1212/WNL.0000000000001153. Epub 2014 Dec 19. Neurology. 2015. PMID: 25527270 Free PMC article. Clinical Trial.
Medical therapies for meningiomas.
Wen PY, Quant E, Drappatz J, Beroukhim R, Norden AD. Wen PY, et al. Among authors: beroukhim r. J Neurooncol. 2010 Sep;99(3):365-78. doi: 10.1007/s11060-010-0349-8. Epub 2010 Sep 4. J Neurooncol. 2010. PMID: 20820875 Review.
Safety of concurrent bevacizumab therapy and anticoagulation in glioma patients.
Norden AD, Bartolomeo J, Tanaka S, Drappatz J, Ciampa AS, Doherty LM, Lafrankie DC, Ruland S, Quant EC, Beroukhim R, Wen PY. Norden AD, et al. Among authors: beroukhim r. J Neurooncol. 2012 Jan;106(1):121-5. doi: 10.1007/s11060-011-0642-1. Epub 2011 Jun 26. J Neurooncol. 2012. PMID: 21706358
Phase I study of panobinostat in combination with bevacizumab for recurrent high-grade glioma.
Drappatz J, Lee EQ, Hammond S, Grimm SA, Norden AD, Beroukhim R, Gerard M, Schiff D, Chi AS, Batchelor TT, Doherty LM, Ciampa AS, Lafrankie DC, Ruland S, Snodgrass SM, Raizer JJ, Wen PY. Drappatz J, et al. Among authors: beroukhim r. J Neurooncol. 2012 Mar;107(1):133-8. doi: 10.1007/s11060-011-0717-z. Epub 2011 Oct 8. J Neurooncol. 2012. PMID: 21984064 Clinical Trial.
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.
Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD, Raza A, Sunkavalli A, Macconaill LE, Stemmer-Rachamimov AO, Louis DN, Hahn WC, Dunn IF, Beroukhim R. Brastianos PK, et al. Among authors: beroukhim r. Nat Genet. 2013 Mar;45(3):285-9. doi: 10.1038/ng.2526. Epub 2013 Jan 20. Nat Genet. 2013. PMID: 23334667 Free PMC article.
Phase 2 study of dose-intense temozolomide in recurrent glioblastoma.
Norden AD, Lesser GJ, Drappatz J, Ligon KL, Hammond SN, Lee EQ, Reardon DR, Fadul CE, Plotkin SR, Batchelor TT, Zhu JJ, Beroukhim R, Muzikansky A, Doherty L, Lafrankie D, Smith K, Tafoya V, Lis R, Stack EC, Rosenfeld MR, Wen PY. Norden AD, et al. Among authors: beroukhim r. Neuro Oncol. 2013 Jul;15(7):930-5. doi: 10.1093/neuonc/not040. Epub 2013 Apr 3. Neuro Oncol. 2013. PMID: 23553268 Free PMC article. Clinical Trial.
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.
Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A, Lawrence MS, Bergthold G, Brastianos PK, Tabak B, Ducar MD, Van Hummelen P, MacConaill LE, Pouissant-Young T, Cho YJ, Taha H, Mahmoud M, Bowers DC, Margraf L, Tabori U, Hawkins C, Packer RJ, Hill DA, Pomeroy SL, Eberhart CG, Dunn IF, Goumnerova L, Getz G, Chan JA, Santagata S, Hahn WC, Stiles CD, Ligon AH, Kieran MW, Beroukhim R, Ligon KL. Ramkissoon LA, et al. Among authors: beroukhim r. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8188-93. doi: 10.1073/pnas.1300252110. Epub 2013 Apr 30. Proc Natl Acad Sci U S A. 2013. PMID: 23633565 Free PMC article.
Update on bevacizumab and other angiogenesis inhibitors for brain cancer.
Rinne ML, Lee EQ, Nayak L, Norden AD, Beroukhim R, Wen PY, Reardon DA. Rinne ML, et al. Among authors: beroukhim r. Expert Opin Emerg Drugs. 2013 Jun;18(2):137-53. doi: 10.1517/14728214.2013.794784. Epub 2013 May 14. Expert Opin Emerg Drugs. 2013. PMID: 23668489 Review.
Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities.
Filbin MG, Dabral SK, Pazyra-Murphy MF, Ramkissoon S, Kung AL, Pak E, Chung J, Theisen MA, Sun Y, Franchetti Y, Sun Y, Shulman DS, Redjal N, Tabak B, Beroukhim R, Wang Q, Zhao J, Dorsch M, Buonamici S, Ligon KL, Kelleher JF, Segal RA. Filbin MG, et al. Among authors: beroukhim r. Nat Med. 2013 Nov;19(11):1518-23. doi: 10.1038/nm.3328. Epub 2013 Sep 29. Nat Med. 2013. PMID: 24076665 Free PMC article.
410 results