Cleary ML - Search Results

1

Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells.

Aikawa Y, Yamagata K, Katsumoto T, Shima Y, Shino M, Stanley ER, Cleary ML, Akashi K, Tenen DG, Kitabayashi I. Aikawa Y, et al. Among authors: cleary ml. Cancer Sci. 2015 Mar;106(3):227-36. doi: 10.1111/cas.12593. Epub 2015 Feb 12. Cancer Sci. 2015. PMID: 25529853 Free PMC article.

2

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.

Yokoyama A, Lin M, Naresh A, Kitabayashi I, Cleary ML. Yokoyama A, et al. Among authors: cleary ml. Cancer Cell. 2010 Feb 17;17(2):198-212. doi: 10.1016/j.ccr.2009.12.040. Cancer Cell. 2010. PMID: 20153263 Free PMC article.

3

Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.

Yokoyama A, Ficara F, Murphy MJ, Meisel C, Naresh A, Kitabayashi I, Cleary ML. Yokoyama A, et al. Among authors: cleary ml. J Cell Sci. 2011 Jul 1;124(Pt 13):2208-19. doi: 10.1242/jcs.080523. J Cell Sci. 2011. PMID: 21670200 Free PMC article.

4

MLL becomes functional through intra-molecular interaction not by proteolytic processing.

Yokoyama A, Ficara F, Murphy MJ, Meisel C, Hatanaka C, Kitabayashi I, Cleary ML. Yokoyama A, et al. Among authors: cleary ml. PLoS One. 2013 Sep 10;8(9):e73649. doi: 10.1371/journal.pone.0073649. eCollection 2013. PLoS One. 2013. PMID: 24040009 Free PMC article.

5

Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties.

Yokoyama A, Kitabayashi I, Ayton PM, Cleary ML, Ohki M. Yokoyama A, et al. Among authors: cleary ml. Blood. 2002 Nov 15;100(10):3710-8. doi: 10.1182/blood-2002-04-1015. Epub 2002 Jun 28. Blood. 2002. PMID: 12393701 Free article.

6

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.

Yokoyama A, Wang Z, Wysocka J, Sanyal M, Aufiero DJ, Kitabayashi I, Herr W, Cleary ML. Yokoyama A, et al. Among authors: cleary ml. Mol Cell Biol. 2004 Jul;24(13):5639-49. doi: 10.1128/MCB.24.13.5639-5649.2004. Mol Cell Biol. 2004. PMID: 15199122 Free PMC article.

7

PU.1 and Junb: suppressing the formation of acute myeloid leukemia stem cells.

Somervaille TC, Cleary ML. Somervaille TC, et al. Among authors: cleary ml. Cancer Cell. 2006 Dec;10(6):456-7. doi: 10.1016/j.ccr.2006.11.009. Cancer Cell. 2006. PMID: 17157786 Free article.

8

The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential.

Wong SH, Goode DL, Iwasaki M, Wei MC, Kuo HP, Zhu L, Schneidawind D, Duque-Afonso J, Weng Z, Cleary ML. Wong SH, et al. Among authors: cleary ml. Cancer Cell. 2015 Aug 10;28(2):198-209. doi: 10.1016/j.ccell.2015.06.003. Epub 2015 Jul 16. Cancer Cell. 2015. PMID: 26190263 Free PMC article.

9

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells.

Somervaille TC, Matheny CJ, Spencer GJ, Iwasaki M, Rinn JL, Witten DM, Chang HY, Shurtleff SA, Downing JR, Cleary ML. Somervaille TC, et al. Among authors: cleary ml. Cell Stem Cell. 2009 Feb 6;4(2):129-40. doi: 10.1016/j.stem.2008.11.015. Cell Stem Cell. 2009. PMID: 19200802 Free PMC article.

10

Grist for the MLL: how do MLL oncogenic fusion proteins generate leukemia stem cells?

Somervaille TC, Cleary ML. Somervaille TC, et al. Among authors: cleary ml. Int J Hematol. 2010 Jun;91(5):735-41. doi: 10.1007/s12185-010-0579-8. Epub 2010 May 8. Int J Hematol. 2010. PMID: 20454944

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