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Systematic identification of signaling pathways with potential to confer anticancer drug resistance.
Martz CA, Ottina KA, Singleton KR, Jasper JS, Wardell SE, Peraza-Penton A, Anderson GR, Winter PS, Wang T, Alley HM, Kwong LN, Cooper ZA, Tetzlaff M, Chen PL, Rathmell JC, Flaherty KT, Wargo JA, McDonnell DP, Sabatini DM, Wood KC. Martz CA, et al. Among authors: mcdonnell dp. Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. Sci Signal. 2014. PMID: 25538079 Free PMC article.
Glucose metabolism as a target of histone deacetylase inhibitors.
Wardell SE, Ilkayeva OR, Wieman HL, Frigo DE, Rathmell JC, Newgard CB, McDonnell DP. Wardell SE, et al. Among authors: mcdonnell dp. Mol Endocrinol. 2009 Mar;23(3):388-401. doi: 10.1210/me.2008-0179. Epub 2008 Dec 23. Mol Endocrinol. 2009. PMID: 19106193 Free PMC article.
The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors.
Nelson ER, DuSell CD, Wang X, Howe MK, Evans G, Michalek RD, Umetani M, Rathmell JC, Khosla S, Gesty-Palmer D, McDonnell DP. Nelson ER, et al. Among authors: mcdonnell dp. Endocrinology. 2011 Dec;152(12):4691-705. doi: 10.1210/en.2011-1298. Epub 2011 Sep 20. Endocrinology. 2011. PMID: 21933863 Free PMC article.
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation.
Michalek RD, Gerriets VA, Nichols AG, Inoue M, Kazmin D, Chang CY, Dwyer MA, Nelson ER, Pollizzi KN, Ilkayeva O, Giguere V, Zuercher WJ, Powell JD, Shinohara ML, McDonnell DP, Rathmell JC. Michalek RD, et al. Among authors: mcdonnell dp. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18348-53. doi: 10.1073/pnas.1108856108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042850 Free PMC article.
298 results