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ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.
Goossens S, Radaelli E, Blanchet O, Durinck K, Van der Meulen J, Peirs S, Taghon T, Tremblay CS, Costa M, Farhang Ghahremani M, De Medts J, Bartunkova S, Haigh K, Schwab C, Farla N, Pieters T, Matthijssens F, Van Roy N, Best JA, Deswarte K, Bogaert P, Carmichael C, Rickard A, Suryani S, Bracken LS, Alserihi R, Canté-Barrett K, Haenebalcke L, Clappier E, Rondou P, Slowicka K, Huylebroeck D, Goldrath AW, Janzen V, McCormack MP, Lock RB, Curtis DJ, Harrison C, Berx G, Speleman F, Meijerink JP, Soulier J, Van Vlierberghe P, Haigh JJ. Goossens S, et al. Among authors: goldrath aw. Nat Commun. 2015 Jan 7;6:5794. doi: 10.1038/ncomms6794. Nat Commun. 2015. PMID: 25565005 Free PMC article.
Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults.
Gong Q, Sharma M, Kuan EL, Glass MC, Chander A, Singh M, Graybuck LT, Thomson ZJ, LaFrance CM, Zaim SR, Peng T, Okada LY, Genge PC, Henderson KE, Dornisch EM, Layton ED, Wittig PJ, Heubeck AT, Mukuka NM, Reading J, Roll CR, Hernandez V, Parthasarathy V, Stuckey TJ, Musgrove B, Swanson E, Lord C, Weiss MDA, Phalen CG, Mettey RR, Lee KJ, Johanneson JB, Kawelo EK, Garber J, Krishnan U, Smithmyer M, Wherry EJ, Vella L, Henrickson SE, Kopp MS, Savage AK, Becker LA, Meijer P, Coffey EM, Goronzy JJ, Speake C, Bumol TF, Goldrath AW, Torgerson TR, Li XJ, Skene PJ, Buckner JH, Gustafson CE. Gong Q, et al. Among authors: goldrath aw. bioRxiv [Preprint]. 2024 Sep 14:2024.09.10.612119. doi: 10.1101/2024.09.10.612119. bioRxiv. 2024. PMID: 39314416 Free PMC article. Preprint.
Systemic inflammation and lymphocyte activation precede rheumatoid arthritis.
He Z, Glass MC, Venkatesan P, Feser ML, Lazaro L, Okada LY, Tran NTT, He YD, Zaim SR, Bennett CE, Ravisankar P, Dornisch EM, Arishi NA, Asamoah AG, Barzideh S, Becker LA, Bemis EA, Buckner JH, Collora CE, Criley MAL, Demoruelle MK, Fleischer CL, Garber J, Genge PC, Gong Q, Graybuck LT, Gustafson CE, Hattel BC, Hernandez V, Heubeck AT, Kawelo EK, Krishnan U, Kuan EL, Kuhn KA, LaFrance CM, Lee KJ, Li R, Lord C, Mettey RR, Moss L, Musgrove B, Nguyen K, Ochoa A, Parthasarathy V, Pebworth MP, Pedrick C, Peng T, Phalen CG, Reading J, Roll CR, Seifert JA, Siedschlag MD, Speake C, Striebich CC, Stuckey TJ, Swanson EG, Takada H, Thai T, Thomson ZJ, Trieu N, Tsaltskan V, Wang W, Weiss MDA, Westermann A, Zhang F, Boyle DL, Goldrath AW, Bumol TF, Li XJ, Holers VM, Skene PJ, Savage AK, Firestein GS, Deane KD, Torgerson TR, Gillespie MA. He Z, et al. Among authors: goldrath aw. bioRxiv [Preprint]. 2024 Nov 12:2024.10.25.620344. doi: 10.1101/2024.10.25.620344. bioRxiv. 2024. PMID: 39554042 Free PMC article. Preprint.
Mll1 pioneers histone H3K4me3 deposition and promotes formation of CD8 + T stem cell memory.
Getzler AJ, Frederick MA, Milner JJ, Venables T, Diao H, Toma C, Nagaraja SD, Albao DS, Bélanger S, Tsuda SM, Kim J, Crotty S, Goldrath AW, Pipkin ME. Getzler AJ, et al. Among authors: goldrath aw. bioRxiv [Preprint]. 2023 Apr 15:2023.01.18.524461. doi: 10.1101/2023.01.18.524461. bioRxiv. 2023. PMID: 37090503 Free PMC article. Preprint.
Transcriptional regulator Id2 mediates CD8+ T cell immunity.
Cannarile MA, Lind NA, Rivera R, Sheridan AD, Camfield KA, Wu BB, Cheung KP, Ding Z, Goldrath AW. Cannarile MA, et al. Among authors: goldrath aw. Nat Immunol. 2006 Dec;7(12):1317-25. doi: 10.1038/ni1403. Epub 2006 Nov 5. Nat Immunol. 2006. PMID: 17086188
Molecular definition of the identity and activation of natural killer cells.
Bezman NA, Kim CC, Sun JC, Min-Oo G, Hendricks DW, Kamimura Y, Best JA, Goldrath AW, Lanier LL; Immunological Genome Project Consortium. Bezman NA, et al. Among authors: goldrath aw. Nat Immunol. 2012 Oct;13(10):1000-9. doi: 10.1038/ni.2395. Epub 2012 Aug 19. Nat Immunol. 2012. PMID: 22902830 Free PMC article.
FOXO transcription factors throughout T cell biology.
Hedrick SM, Hess Michelini R, Doedens AL, Goldrath AW, Stone EL. Hedrick SM, et al. Among authors: goldrath aw. Nat Rev Immunol. 2012 Sep;12(9):649-61. doi: 10.1038/nri3278. Nat Rev Immunol. 2012. PMID: 22918467 Free PMC article. Review.
135 results