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Saireito (TJ-114), a Japanese traditional herbal medicine, reduces 5-fluorouracil-induced intestinal mucositis in mice by inhibiting cytokine-mediated apoptosis in intestinal crypt cells.
Kato S, Hayashi S, Kitahara Y, Nagasawa K, Aono H, Shibata J, Utsumi D, Amagase K, Kadowaki M. Kato S, et al. Among authors: kadowaki m. PLoS One. 2015 Jan 7;10(1):e0116213. doi: 10.1371/journal.pone.0116213. eCollection 2015. PLoS One. 2015. PMID: 25565296 Free PMC article.
The traditional herbal medicine saireito exerts its inhibitory effect on murine oxazolone-induced colitis via the induction of Th1-polarized immune responses in the mucosal immune system of the colon.
Watanabe T, Yamamoto T, Yoshida M, Fujiwara K, Kageyama-Yahara N, Kuramoto H, Shimada Y, Kadowaki M. Watanabe T, et al. Among authors: kadowaki m. Int Arch Allergy Immunol. 2010;151(2):98-106. doi: 10.1159/000235999. Epub 2009 Sep 15. Int Arch Allergy Immunol. 2010. PMID: 19752563
Shikonin, a constituent of Lithospermum erythrorhizon exhibits anti-allergic effects by suppressing orphan nuclear receptor Nr4a family gene expression as a new prototype of calcineurin inhibitors in mast cells.
Wang X, Hayashi S, Umezaki M, Yamamoto T, Kageyama-Yahara N, Kondo T, Kadowaki M. Wang X, et al. Among authors: kadowaki m. Chem Biol Interact. 2014 Dec 5;224:117-27. doi: 10.1016/j.cbi.2014.10.021. Epub 2014 Oct 29. Chem Biol Interact. 2014. PMID: 25451590
429 results