Lein PJ - Search Results

1

Rapid throughput analysis demonstrates that chemicals with distinct seizurogenic mechanisms differentially alter Ca2+ dynamics in networks formed by hippocampal neurons in culture.

Cao Z, Zou X, Cui Y, Hulsizer S, Lein PJ, Wulff H, Pessah IN. Cao Z, et al. Among authors: lein pj. Mol Pharmacol. 2015 Apr;87(4):595-605. doi: 10.1124/mol.114.096701. Epub 2015 Jan 12. Mol Pharmacol. 2015. PMID: 25583085 Free PMC article.

2

Polychlorinated biphenyls induce caspase-dependent cell death in cultured embryonic rat hippocampal but not cortical neurons via activation of the ryanodine receptor.

Howard AS, Fitzpatrick R, Pessah I, Kostyniak P, Lein PJ. Howard AS, et al. Among authors: lein pj. Toxicol Appl Pharmacol. 2003 Jul 1;190(1):72-86. doi: 10.1016/s0041-008x(03)00156-x. Toxicol Appl Pharmacol. 2003. PMID: 12831785

3

Immunologic and neurodevelopmental susceptibilities of autism.

Pessah IN, Seegal RF, Lein PJ, LaSalle J, Yee BK, Van De Water J, Berman RF. Pessah IN, et al. Among authors: lein pj. Neurotoxicology. 2008 May;29(3):532-45. doi: 10.1016/j.neuro.2008.02.006. Epub 2008 Feb 23. Neurotoxicology. 2008. PMID: 18394707 Free PMC article. Review.

4

Minding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicity.

Pessah IN, Cherednichenko G, Lein PJ. Pessah IN, et al. Among authors: lein pj. Pharmacol Ther. 2010 Feb;125(2):260-85. doi: 10.1016/j.pharmthera.2009.10.009. Epub 2009 Nov 25. Pharmacol Ther. 2010. PMID: 19931307 Free PMC article. Review.

5

Para- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicity.

Kim KH, Bose DD, Ghogha A, Riehl J, Zhang R, Barnhart CD, Lein PJ, Pessah IN. Kim KH, et al. Among authors: lein pj. Environ Health Perspect. 2011 Apr;119(4):519-26. doi: 10.1289/ehp.1002728. Epub 2010 Nov 24. Environ Health Perspect. 2011. PMID: 21106467 Free PMC article.

6

Acute hippocampal slice preparation and hippocampal slice cultures.

Lein PJ, Barnhart CD, Pessah IN. Lein PJ, et al. Methods Mol Biol. 2011;758:115-34. doi: 10.1007/978-1-61779-170-3_8. Methods Mol Biol. 2011. PMID: 21815062 Free PMC article.

7

PCB-95 promotes dendritic growth via ryanodine receptor-dependent mechanisms.

Wayman GA, Yang D, Bose DD, Lesiak A, Ledoux V, Bruun D, Pessah IN, Lein PJ. Wayman GA, et al. Among authors: lein pj. Environ Health Perspect. 2012 Jul;120(7):997-1002. doi: 10.1289/ehp.1104832. Epub 2012 Apr 25. Environ Health Perspect. 2012. PMID: 22534141 Free PMC article.

8

PCB-95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendritic growth.

Wayman GA, Bose DD, Yang D, Lesiak A, Bruun D, Impey S, Ledoux V, Pessah IN, Lein PJ. Wayman GA, et al. Among authors: lein pj. Environ Health Perspect. 2012 Jul;120(7):1003-9. doi: 10.1289/ehp.1104833. Epub 2012 Apr 25. Environ Health Perspect. 2012. PMID: 22534176 Free PMC article.

9

Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation.

Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN. Cao Z, et al. Among authors: lein pj. Toxicol Sci. 2012 Dec;130(2):362-72. doi: 10.1093/toxsci/kfs244. Epub 2012 Aug 13. Toxicol Sci. 2012. PMID: 22889812 Free PMC article.

10

PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanisms.

Yang D, Kania-Korwel I, Ghogha A, Chen H, Stamou M, Bose DD, Pessah IN, Lehmler HJ, Lein PJ. Yang D, et al. Among authors: lein pj. Toxicol Sci. 2014 Apr;138(2):379-92. doi: 10.1093/toxsci/kft334. Epub 2014 Jan 2. Toxicol Sci. 2014. PMID: 24385416 Free PMC article.

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