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Page 1
Mycobacterium tuberculosis gyrase inhibitors as a new class of antitubercular drugs.
Blanco D, Perez-Herran E, Cacho M, Ballell L, Castro J, González Del Río R, Lavandera JL, Remuiñán MJ, Richards C, Rullas J, Vázquez-Muñiz MJ, Woldu E, Zapatero-González MC, Angulo-Barturen I, Mendoza A, Barros D. Blanco D, et al. Among authors: lavandera jl. Antimicrob Agents Chemother. 2015 Apr;59(4):1868-75. doi: 10.1128/AAC.03913-14. Epub 2015 Jan 12. Antimicrob Agents Chemother. 2015. PMID: 25583730 Free PMC article.
Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis.
Ballell L, Bates RH, Young RJ, Alvarez-Gomez D, Alvarez-Ruiz E, Barroso V, Blanco D, Crespo B, Escribano J, González R, Lozano S, Huss S, Santos-Villarejo A, Martín-Plaza JJ, Mendoza A, Rebollo-Lopez MJ, Remuiñan-Blanco M, Lavandera JL, Pérez-Herran E, Gamo-Benito FJ, García-Bustos JF, Barros D, Castro JP, Cammack N. Ballell L, et al. Among authors: lavandera jl. ChemMedChem. 2013 Feb;8(2):313-21. doi: 10.1002/cmdc.201200428. Epub 2013 Jan 10. ChemMedChem. 2013. PMID: 23307663 Free PMC article.
Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor.
Martínez-Hoyos M, Perez-Herran E, Gulten G, Encinas L, Álvarez-Gómez D, Alvarez E, Ferrer-Bazaga S, García-Pérez A, Ortega F, Angulo-Barturen I, Rullas-Trincado J, Blanco Ruano D, Torres P, Castañeda P, Huss S, Fernández Menéndez R, González Del Valle S, Ballell L, Barros D, Modha S, Dhar N, Signorino-Gelo F, McKinney JD, García-Bustos JF, Lavandera JL, Sacchettini JC, Jimenez MS, Martín-Casabona N, Castro-Pichel J, Mendoza-Losana A. Martínez-Hoyos M, et al. Among authors: lavandera jl. EBioMedicine. 2016 Jun;8:291-301. doi: 10.1016/j.ebiom.2016.05.006. Epub 2016 May 8. EBioMedicine. 2016. PMID: 27428438 Free PMC article.
Functional screening of selective mitochondrial inhibitors of Plasmodium.
Gomez-Lorenzo MG, Rodríguez-Alejandre A, Moliner-Cubel S, Martínez-Hoyos M, Bahamontes-Rosa N, Gonzalez Del Rio R, Ródenas C, Fuente J, Lavandera JL, García-Bustos JF, Mendoza-Losana A. Gomez-Lorenzo MG, et al. Among authors: lavandera jl. Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):295-303. doi: 10.1016/j.ijpddr.2018.04.007. Epub 2018 May 9. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29775797 Free PMC article.
An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS.
Calderón F, Barros D, Bueno JM, Coterón JM, Fernández E, Gamo FJ, Lavandera JL, León ML, Macdonald SJ, Mallo A, Manzano P, Porras E, Fiandor JM, Castro J. Calderón F, et al. Among authors: lavandera jl. ACS Med Chem Lett. 2011 Aug 3;2(10):741-6. doi: 10.1021/ml200135p. eCollection 2011 Oct 13. ACS Med Chem Lett. 2011. PMID: 24900261 Free PMC article.
Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity.
Cameron A, Read J, Tranter R, Winter VJ, Sessions RB, Brady RL, Vivas L, Easton A, Kendrick H, Croft SL, Barros D, Lavandera JL, Martin JJ, Risco F, García-Ochoa S, Gamo FJ, Sanz L, Leon L, Ruiz JR, Gabarró R, Mallo A, Gómez de las Heras F. Cameron A, et al. Among authors: lavandera jl. J Biol Chem. 2004 Jul 23;279(30):31429-39. doi: 10.1074/jbc.M402433200. Epub 2004 Apr 26. J Biol Chem. 2004. PMID: 15117937 Free article.
Thousands of chemical starting points for antimalarial lead identification.
Gamo FJ, Sanz LM, Vidal J, de Cozar C, Alvarez E, Lavandera JL, Vanderwall DE, Green DV, Kumar V, Hasan S, Brown JR, Peishoff CE, Cardon LR, Garcia-Bustos JF. Gamo FJ, et al. Among authors: lavandera jl. Nature. 2010 May 20;465(7296):305-10. doi: 10.1038/nature09107. Nature. 2010. PMID: 20485427
26 results