Hart DJ - Search Results

1

Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7.

Pumroy RA, Ke S, Hart DJ, Zachariae U, Cingolani G. Pumroy RA, et al. Among authors: hart dj. Structure. 2015 Feb 3;23(2):374-84. doi: 10.1016/j.str.2014.11.015. Epub 2015 Jan 15. Structure. 2015. PMID: 25599645 Free PMC article.

2

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.

Tarendeau F, Boudet J, Guilligay D, Mas PJ, Bougault CM, Boulo S, Baudin F, Ruigrok RW, Daigle N, Ellenberg J, Cusack S, Simorre JP, Hart DJ. Tarendeau F, et al. Among authors: hart dj. Nat Struct Mol Biol. 2007 Mar;14(3):229-33. doi: 10.1038/nsmb1212. Epub 2007 Feb 25. Nat Struct Mol Biol. 2007. PMID: 17310249

3

The structural basis for cap binding by influenza virus polymerase subunit PB2.

Guilligay D, Tarendeau F, Resa-Infante P, Coloma R, Crepin T, Sehr P, Lewis J, Ruigrok RW, Ortin J, Hart DJ, Cusack S. Guilligay D, et al. Among authors: hart dj. Nat Struct Mol Biol. 2008 May;15(5):500-6. doi: 10.1038/nsmb.1421. Epub 2008 May 4. Nat Struct Mol Biol. 2008. PMID: 18454157

4

Host determinant residue lysine 627 lies on the surface of a discrete, folded domain of influenza virus polymerase PB2 subunit.

Tarendeau F, Crepin T, Guilligay D, Ruigrok RW, Cusack S, Hart DJ. Tarendeau F, et al. Among authors: hart dj. PLoS Pathog. 2008 Aug 29;4(8):e1000136. doi: 10.1371/journal.ppat.1000136. PLoS Pathog. 2008. PMID: 18769709 Free PMC article.

5

Interaction of the influenza A virus polymerase PB2 C-terminal region with importin alpha isoforms provides insights into host adaptation and polymerase assembly.

Boivin S, Hart DJ. Boivin S, et al. Among authors: hart dj. J Biol Chem. 2011 Mar 25;286(12):10439-48. doi: 10.1074/jbc.M110.182964. Epub 2011 Jan 7. J Biol Chem. 2011. PMID: 21216958 Free PMC article.

6

Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin α5.

Pumroy RA, Nardozzi JD, Hart DJ, Root MJ, Cingolani G. Pumroy RA, et al. Among authors: hart dj. J Biol Chem. 2012 Jan 13;287(3):2022-31. doi: 10.1074/jbc.M111.315838. Epub 2011 Nov 30. J Biol Chem. 2012. PMID: 22130666 Free PMC article.

7

Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin α.

Delaforge E, Milles S, Bouvignies G, Bouvier D, Boivin S, Salvi N, Maurin D, Martel A, Round A, Lemke EA, Jensen MR, Hart DJ, Blackledge M. Delaforge E, et al. Among authors: hart dj. J Am Chem Soc. 2015 Dec 9;137(48):15122-34. doi: 10.1021/jacs.5b07765. Epub 2015 Oct 16. J Am Chem Soc. 2015. PMID: 26424125

8

Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.

Thierry E, Guilligay D, Kosinski J, Bock T, Gaudon S, Round A, Pflug A, Hengrung N, El Omari K, Baudin F, Hart DJ, Beck M, Cusack S. Thierry E, et al. Among authors: hart dj. Mol Cell. 2016 Jan 7;61(1):125-37. doi: 10.1016/j.molcel.2015.11.016. Epub 2015 Dec 17. Mol Cell. 2016. PMID: 26711008 Free PMC article.

9

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites.

Simon B, Huart AS, Temmerman K, Vahokoski J, Mertens HD, Komadina D, Hoffmann JE, Yumerefendi H, Svergun DI, Kursula P, Schultz C, McCarthy AA, Hart DJ, Wilmanns M. Simon B, et al. Among authors: hart dj. Structure. 2016 Jun 7;24(6):851-61. doi: 10.1016/j.str.2016.03.020. Epub 2016 Apr 28. Structure. 2016. PMID: 27133022 Free PMC article.

10

Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A.

Camacho-Zarco AR, Kalayil S, Maurin D, Salvi N, Delaforge E, Milles S, Jensen MR, Hart DJ, Cusack S, Blackledge M. Camacho-Zarco AR, et al. Among authors: hart dj. Nat Commun. 2020 Jul 21;11(1):3656. doi: 10.1038/s41467-020-17407-x. Nat Commun. 2020. PMID: 32694517 Free PMC article.

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