O'Hagan DT - Search Results

1

The development of self-emulsifying oil-in-water emulsion adjuvant and an evaluation of the impact of droplet size on performance.

Shah RR, Dodd S, Schaefer M, Ugozzoli M, Singh M, Otten GR, Amiji MM, O'Hagan DT, Brito LA. Shah RR, et al. J Pharm Sci. 2015 Apr;104(4):1352-61. doi: 10.1002/jps.24337. Epub 2015 Jan 19. J Pharm Sci. 2015. PMID: 25600347

2

The impact of size on particulate vaccine adjuvants.

Shah RR, O'Hagan DT, Amiji MM, Brito LA. Shah RR, et al. Nanomedicine (Lond). 2014 Dec;9(17):2671-81. doi: 10.2217/nnm.14.193. Nanomedicine (Lond). 2014. PMID: 25529570

3

Stable Nanoemulsions for the Delivery of Small Molecule Immune Potentiators.

Lodaya RN, Brito LA, Wu TYH, Miller AT, Otten GR, Singh M, O'Hagan DT. Lodaya RN, et al. J Pharm Sci. 2018 Sep;107(9):2310-2314. doi: 10.1016/j.xphs.2018.05.012. Epub 2018 Jun 5. J Pharm Sci. 2018. PMID: 29883663

4

The droplet size of emulsion adjuvants has significant impact on their potency, due to differences in immune cell-recruitment and -activation.

Shah RR, Taccone M, Monaci E, Brito LA, Bonci A, O'Hagan DT, Amiji MM, Seubert A. Shah RR, et al. Sci Rep. 2019 Aug 8;9(1):11520. doi: 10.1038/s41598-019-47885-z. Sci Rep. 2019. PMID: 31395915 Free PMC article.

5

Recent advances in vaccine adjuvants.

Singh M, O'Hagan DT. Singh M, et al. Pharm Res. 2002 Jun;19(6):715-28. doi: 10.1023/a:1016104910582. Pharm Res. 2002. PMID: 12134940 Review.

6

A two-stage strategy for sterilization of poly(lactide-co-glycolide) particles by γ-irradiation does not impair their potency for vaccine delivery.

Jain S, Malyala P, Pallaoro M, Giuliani M, Petersen H, O'Hagan DT, Singh M. Jain S, et al. J Pharm Sci. 2011 Feb;100(2):646-54. doi: 10.1002/jps.22306. J Pharm Sci. 2011. PMID: 20665902

7

An alternative renewable source of squalene for use in emulsion adjuvants.

Brito LA, Chan M, Baudner B, Gallorini S, Santos G, O'Hagan DT, Singh M. Brito LA, et al. Vaccine. 2011 Aug 26;29(37):6262-8. doi: 10.1016/j.vaccine.2011.06.067. Epub 2011 Jun 30. Vaccine. 2011. PMID: 21723355

8

A cationic nanoemulsion for the delivery of next-generation RNA vaccines.

Brito LA, Chan M, Shaw CA, Hekele A, Carsillo T, Schaefer M, Archer J, Seubert A, Otten GR, Beard CW, Dey AK, Lilja A, Valiante NM, Mason PW, Mandl CW, Barnett SW, Dormitzer PR, Ulmer JB, Singh M, O'Hagan DT, Geall AJ. Brito LA, et al. Mol Ther. 2014 Dec;22(12):2118-2129. doi: 10.1038/mt.2014.133. Epub 2014 Jul 16. Mol Ther. 2014. PMID: 25027661 Free PMC article.

9

The Preparation and Physicochemical Characterization of Aluminum Hydroxide/TLR7a, a Novel Vaccine Adjuvant Comprising a Small Molecule Adsorbed to Aluminum Hydroxide.

Malyala P, Laera D, Cianetti S, Bufali S, Aggravi M, Ianni E, Judge C, Otten G, Singh M, O'Hagan DT. Malyala P, et al. J Pharm Sci. 2018 Jun;107(6):1577-1585. doi: 10.1016/j.xphs.2018.01.024. Epub 2018 Feb 6. J Pharm Sci. 2018. PMID: 29421216

10

Formulation Design, Optimization and In Vivo Evaluations of an α-Tocopherol-Containing Self-Emulsified Adjuvant System using Inactivated Influenza Vaccine.

Lodaya RN, Kanitkar AP, Friedrich K, Henson D, Yamagata R, Nuti S, Mallett CP, Bertholet S, Amiji MM, O'Hagan DT. Lodaya RN, et al. J Control Release. 2019 Dec 28;316:12-21. doi: 10.1016/j.jconrel.2019.10.042. Epub 2019 Oct 31. J Control Release. 2019. PMID: 31678654 Free article.

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