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Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A.
Strilchuk AW, Hur WS, Batty P, Sang Y, Abrahams SR, Yong ASM, Leung J, Silva LM, Schroeder JA, Nesbitt K, de Laat B, Moutsopoulos NM, Bugge TH, Shi Q, Cullis PR, Merricks EP, Wolberg AS, Flick MJ, Lillicrap D, Nichols TC, Kastrup CJ. Strilchuk AW, et al. Among authors: moutsopoulos nm. Sci Transl Med. 2024 Feb 21;16(735):eadh0027. doi: 10.1126/scitranslmed.adh0027. Epub 2024 Feb 21. Sci Transl Med. 2024. PMID: 38381848 Free PMC article.
Neutrophils are gatekeepers of mucosal immunity.
Silva LM, Kim TS, Moutsopoulos NM. Silva LM, et al. Among authors: moutsopoulos nm. Immunol Rev. 2023 Mar;314(1):125-141. doi: 10.1111/imr.13171. Epub 2022 Nov 20. Immunol Rev. 2023. PMID: 36404627 Free PMC article. Review.
Matched related and unrelated donor hematopoietic stem cell transplantation for DOCK8 deficiency.
Cuellar-Rodriguez J, Freeman AF, Grossman J, Su H, Parta M, Murdock H, Shah N, Bollard C, Kong HH, Moutsopoulos N, Stone K, Gea-Banacloche J, Holland SM, Hickstein DD. Cuellar-Rodriguez J, et al. Biol Blood Marrow Transplant. 2015 Jun;21(6):1037-45. doi: 10.1016/j.bbmt.2015.01.022. Epub 2015 Jan 27. Biol Blood Marrow Transplant. 2015. PMID: 25636378 Free PMC article. Clinical Trial.
Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.
Falcone EL, Abusleme L, Swamydas M, Lionakis MS, Ding L, Hsu AP, Zelazny AM, Moutsopoulos NM, Kuhns DB, Deming C, Quiñones M, Segre JA, Bryant CE, Holland SM. Falcone EL, et al. Among authors: moutsopoulos nm. Microbiome. 2016 Apr 5;4:13. doi: 10.1186/s40168-016-0159-0. Microbiome. 2016. PMID: 27044504 Free PMC article.
95 results