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A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling.
Kong B, Wu W, Cheng T, Schlitter AM, Qian C, Bruns P, Jian Z, Jäger C, Regel I, Raulefs S, Behler N, Irmler M, Beckers J, Friess H, Erkan M, Siveke JT, Tannapfel A, Hahn SA, Theis FJ, Esposito I, Kleeff J, Michalski CW. Kong B, et al. Among authors: raulefs s. Gut. 2016 Apr;65(4):647-57. doi: 10.1136/gutjnl-2014-307616. Epub 2015 Jan 19. Gut. 2016. PMID: 25601637
Energy metabolism and proliferation in pancreatic carcinogenesis.
Regel I, Kong B, Raulefs S, Erkan M, Michalski CW, Hartel M, Kleeff J. Regel I, et al. Among authors: raulefs s. Langenbecks Arch Surg. 2012 Apr;397(4):507-12. doi: 10.1007/s00423-012-0933-9. Epub 2012 Mar 20. Langenbecks Arch Surg. 2012. PMID: 22430298 Review.
Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy.
Kong B, Bruns P, Behler NA, Chang L, Schlitter AM, Cao J, Gewies A, Ruland J, Fritzsche S, Valkovskaya N, Jian Z, Regel I, Raulefs S, Irmler M, Beckers J, Friess H, Erkan M, Mueller NS, Roth S, Hackert T, Esposito I, Theis FJ, Kleeff J, Michalski CW. Kong B, et al. Among authors: raulefs s. Gut. 2018 Jan;67(1):146-156. doi: 10.1136/gutjnl-2015-310913. Epub 2016 Sep 19. Gut. 2018. PMID: 27646934
Glycemic Variability Promotes Both Local Invasion and Metastatic Colonization by Pancreatic Ductal Adenocarcinoma.
Jian Z, Cheng T, Zhang Z, Raulefs S, Shi K, Steiger K, Maeritz N, Kleigrewe K, Hofmann T, Benitz S, Bruns P, Lamp D, Jastroch M, Akkan J, Jäger C, Huang P, Nie S, Shen S, Zou X, Ceyhan GO, Michalski CW, Friess H, Kleeff J, Kong B. Jian Z, et al. Among authors: raulefs s. Cell Mol Gastroenterol Hepatol. 2018 Jul 26;6(4):429-449. doi: 10.1016/j.jcmgh.2018.07.003. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30258965 Free PMC article.
25 results