Dekker LV - Search Results

1

Coagulation factor XII protease domain crystal structure.

Pathak M, Wilmann P, Awford J, Li C, Hamad BK, Fischer PM, Dreveny I, Dekker LV, Emsley J. Pathak M, et al. Among authors: dekker lv. J Thromb Haemost. 2015 Apr;13(4):580-91. doi: 10.1111/jth.12849. Epub 2015 Mar 11. J Thromb Haemost. 2015. PMID: 25604127 Free PMC article.

2

A Cy5-labeled S100A10 tracer used to identify inhibitors of the protein interaction with annexin A2.

Li C, Reddy TR, Fischer PM, Dekker LV. Li C, et al. Among authors: dekker lv. Assay Drug Dev Technol. 2010 Feb;8(1):85-95. doi: 10.1089/adt.2009.0218. Assay Drug Dev Technol. 2010. PMID: 20085458

3

Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines.

Mohammed MZ, Vyjayanti VN, Laughton CA, Dekker LV, Fischer PM, Wilson DM 3rd, Abbotts R, Shah S, Patel PM, Hickson ID, Madhusudan S. Mohammed MZ, et al. Among authors: dekker lv. Br J Cancer. 2011 Feb 15;104(4):653-63. doi: 10.1038/sj.bjc.6606058. Epub 2011 Jan 25. Br J Cancer. 2011. PMID: 21266972 Free PMC article.

4

Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction.

Reddy TR, Li C, Guo X, Myrvang HK, Fischer PM, Dekker LV. Reddy TR, et al. Among authors: dekker lv. J Med Chem. 2011 Apr 14;54(7):2080-94. doi: 10.1021/jm101212e. Epub 2011 Mar 4. J Med Chem. 2011. PMID: 21375334 Free PMC article.

5

Three-dimensional pharmacophore design and biochemical screening identifies substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction.

Reddy TR, Li C, Fischer PM, Dekker LV. Reddy TR, et al. Among authors: dekker lv. ChemMedChem. 2012 Aug;7(8):1435-46. doi: 10.1002/cmdc.201200107. Epub 2012 May 29. ChemMedChem. 2012. PMID: 22644793 Free PMC article.

6

Protein interactions between surface annexin A2 and S100A10 mediate adhesion of breast cancer cells to microvascular endothelial cells.

Myrvang HK, Guo X, Li C, Dekker LV. Myrvang HK, et al. Among authors: dekker lv. FEBS Lett. 2013 Oct 1;587(19):3210-5. doi: 10.1016/j.febslet.2013.08.012. Epub 2013 Aug 27. FEBS Lett. 2013. PMID: 23994525 Free article.

7

Design, synthesis and SAR exploration of tri-substituted 1,2,4-triazoles as inhibitors of the annexin A2-S100A10 protein interaction.

Reddy TR, Li C, Guo X, Fischer PM, Dekker LV. Reddy TR, et al. Among authors: dekker lv. Bioorg Med Chem. 2014 Oct 1;22(19):5378-91. doi: 10.1016/j.bmc.2014.07.043. Epub 2014 Aug 7. Bioorg Med Chem. 2014. PMID: 25172147 Free PMC article.

8

Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation.

Hamad BK, Pathak M, Manna R, Fischer PM, Emsley J, Dekker LV. Hamad BK, et al. Among authors: dekker lv. J Thromb Haemost. 2017 Sep;15(9):1818-1828. doi: 10.1111/jth.13773. Epub 2017 Aug 9. J Thromb Haemost. 2017. PMID: 28688220 Free PMC article.

9

Crystal structures of the recombinant β-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics.

Pathak M, Manna R, Li C, Kaira BG, Hamad BK, Belviso BD, Bonturi CR, Dreveny I, Fischer PM, Dekker LV, Oliva MLV, Emsley J. Pathak M, et al. Among authors: dekker lv. Acta Crystallogr D Struct Biol. 2019 Jun 1;75(Pt 6):578-591. doi: 10.1107/S2059798319006910. Epub 2019 Jun 4. Acta Crystallogr D Struct Biol. 2019. PMID: 31205020

10

Crystal structure of the C2 domain from protein kinase C-delta.

Pappa H, Murray-Rust J, Dekker LV, Parker PJ, McDonald NQ. Pappa H, et al. Among authors: dekker lv. Structure. 1998 Jul 15;6(7):885-94. doi: 10.1016/s0969-2126(98)00090-2. Structure. 1998. PMID: 9687370 Free article.

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