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The cytoskeleton regulatory protein hMena (ENAH) is overexpressed in human benign breast lesions with high risk of transformation and human epidermal growth factor receptor-2-positive/hormonal receptor-negative tumors.
Di Modugno F, Mottolese M, Di Benedetto A, Conidi A, Novelli F, Perracchio L, Venturo I, Botti C, Jager E, Santoni A, Natali PG, Nisticò P. Di Modugno F, et al. Among authors: nistico p. Clin Cancer Res. 2006 Mar 1;12(5):1470-8. doi: 10.1158/1078-0432.CCR-05-2027. Clin Cancer Res. 2006. PMID: 16533770 Free article.
Molecular cloning of hMena (ENAH) and its splice variant hMena+11a: epidermal growth factor increases their expression and stimulates hMena+11a phosphorylation in breast cancer cell lines.
Di Modugno F, DeMonte L, Balsamo M, Bronzi G, Nicotra MR, Alessio M, Jager E, Condeelis JS, Santoni A, Natali PG, Nisticò P. Di Modugno F, et al. Among authors: nistico p. Cancer Res. 2007 Mar 15;67(6):2657-65. doi: 10.1158/0008-5472.CAN-06-1997. Cancer Res. 2007. PMID: 17363586 Free PMC article.
Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines.
Pino MS, Balsamo M, Di Modugno F, Mottolese M, Alessio M, Melucci E, Milella M, McConkey DJ, Philippar U, Gertler FB, Natali PG, Nisticò P. Pino MS, et al. Among authors: nistico p. Clin Cancer Res. 2008 Aug 1;14(15):4943-50. doi: 10.1158/1078-0432.CCR-08-0436. Clin Cancer Res. 2008. PMID: 18676769 Free PMC article.
88 results