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Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance.
Henstridge DC, Estevez E, Allen TL, Heywood SE, Gardner T, Yang C, Mellett NA, Kingwell BA, Meikle PJ, Febbraio MA. Henstridge DC, et al. Among authors: febbraio ma. Cell Stress Chaperones. 2015 May;20(3):461-72. doi: 10.1007/s12192-015-0571-6. Epub 2015 Jan 25. Cell Stress Chaperones. 2015. PMID: 25618331 Free PMC article.
Exercise increases serum Hsp72 in humans.
Walsh RC, Koukoulas I, Garnham A, Moseley PL, Hargreaves M, Febbraio MA. Walsh RC, et al. Among authors: febbraio ma. Cell Stress Chaperones. 2001 Oct;6(4):386-93. doi: 10.1379/1466-1268(2001)006<0386:eishih>2.0.co;2. Cell Stress Chaperones. 2001. PMID: 11795476 Free PMC article.
HSP72 protects against obesity-induced insulin resistance.
Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA. Chung J, et al. Among authors: febbraio ma. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1739-44. doi: 10.1073/pnas.0705799105. Epub 2008 Jan 25. Proc Natl Acad Sci U S A. 2008. PMID: 18223156 Free PMC article.
Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression.
Yuen DY, Dwyer RM, Matthews VB, Zhang L, Drew BG, Neill B, Kingwell BA, Clark MG, Rattigan S, Febbraio MA. Yuen DY, et al. Among authors: febbraio ma. Diabetes. 2009 May;58(5):1086-95. doi: 10.2337/db08-0775. Epub 2009 Feb 2. Diabetes. 2009. PMID: 19188427 Free PMC article.
High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus.
Drew BG, Duffy SJ, Formosa MF, Natoli AK, Henstridge DC, Penfold SA, Thomas WG, Mukhamedova N, de Courten B, Forbes JM, Yap FY, Kaye DM, van Hall G, Febbraio MA, Kemp BE, Sviridov D, Steinberg GR, Kingwell BA. Drew BG, et al. Among authors: febbraio ma. Circulation. 2009 Apr 21;119(15):2103-11. doi: 10.1161/CIRCULATIONAHA.108.843219. Epub 2009 Apr 6. Circulation. 2009. PMID: 19349317 Clinical Trial.
297 results