Jaeschke H - Search Results

1

Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.

Woolbright BL, Dorko K, Antoine DJ, Clarke JI, Gholami P, Li F, Kumer SC, Schmitt TM, Forster J, Fan F, Jenkins RE, Park BK, Hagenbuch B, Olyaee M, Jaeschke H. Woolbright BL, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2015 Mar 15;283(3):168-77. doi: 10.1016/j.taap.2015.01.015. Epub 2015 Jan 28. Toxicol Appl Pharmacol. 2015. PMID: 25636263 Free PMC article.

2

Acetaminophen-induced inhibition of Fas receptor-mediated liver cell apoptosis: mitochondrial dysfunction versus glutathione depletion.

Knight TR, Jaeschke H. Knight TR, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2002 Jun 1;181(2):133-41. doi: 10.1006/taap.2002.9407. Toxicol Appl Pharmacol. 2002. PMID: 12051997

3

Oncotic necrosis and caspase-dependent apoptosis during galactosamine-induced liver injury in rats.

Gujral JS, Farhood A, Jaeschke H. Gujral JS, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2003 Jul 1;190(1):37-46. doi: 10.1016/s0041-008x(03)00154-6. Toxicol Appl Pharmacol. 2003. PMID: 12831781

4

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

Saito C, Yan HM, Artigues A, Villar MT, Farhood A, Jaeschke H. Saito C, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2010 Jan 15;242(2):182-90. doi: 10.1016/j.taap.2009.10.006. Epub 2009 Oct 14. Toxicol Appl Pharmacol. 2010. PMID: 19835899 Free PMC article.

5

Oxidative stress and the pathogenesis of cholestasis.

Copple BL, Jaeschke H, Klaassen CD. Copple BL, et al. Among authors: jaeschke h. Semin Liver Dis. 2010 May;30(2):195-204. doi: 10.1055/s-0030-1253228. Epub 2010 Apr 26. Semin Liver Dis. 2010. PMID: 20422501 Review.

6

c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity.

Saito C, Lemasters JJ, Jaeschke H. Saito C, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2010 Jul;246(1-2):8-17. doi: 10.1016/j.taap.2010.04.015. Epub 2010 Apr 25. Toxicol Appl Pharmacol. 2010. PMID: 20423716 Free PMC article.

7

The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes.

Yan HM, Ramachandran A, Bajt ML, Lemasters JJ, Jaeschke H. Yan HM, et al. Among authors: jaeschke h. Toxicol Sci. 2010 Oct;117(2):515-23. doi: 10.1093/toxsci/kfq208. Epub 2010 Jul 8. Toxicol Sci. 2010. PMID: 20616211 Free PMC article.

8

Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury.

Williams CD, Farhood A, Jaeschke H. Williams CD, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2010 Sep 15;247(3):169-78. doi: 10.1016/j.taap.2010.07.004. Epub 2010 Jul 15. Toxicol Appl Pharmacol. 2010. PMID: 20637792 Free PMC article.

9

Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice.

Luyendyk JP, Flanagan KC, Williams CD, Jaeschke H, Slusser JG, Mackman N, Cantor GH. Luyendyk JP, et al. Among authors: jaeschke h. Toxicol Appl Pharmacol. 2011 Feb 1;250(3):256-62. doi: 10.1016/j.taap.2010.11.002. Epub 2010 Nov 9. Toxicol Appl Pharmacol. 2011. PMID: 21070799 Free PMC article.

10

Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis.

Allen K, Jaeschke H, Copple BL. Allen K, et al. Among authors: jaeschke h. Am J Pathol. 2011 Jan;178(1):175-86. doi: 10.1016/j.ajpath.2010.11.026. Epub 2010 Dec 23. Am J Pathol. 2011. PMID: 21224055 Free PMC article.

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