Poellinger L - Search Results

1

Activation of protein phosphatase 2A tumor suppressor as potential treatment of pancreatic cancer.

Chien W, Sun QY, Lee KL, Ding LW, Wuensche P, Torres-Fernandez LA, Tan SZ, Tokatly I, Zaiden N, Poellinger L, Mori S, Yang H, Tyner JW, Koeffler HP. Chien W, et al. Among authors: poellinger l. Mol Oncol. 2015 Apr;9(4):889-905. doi: 10.1016/j.molonc.2015.01.002. Epub 2015 Jan 15. Mol Oncol. 2015. PMID: 25637283 Free PMC article.

2

Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells.

Chien W, Ding LW, Sun QY, Torres-Fernandez LA, Tan SZ, Xiao J, Lim SL, Garg M, Lee KL, Kitajima S, Takao S, Leong WZ, Sun H, Tokatly I, Poellinger L, Gery S, Koeffler PH. Chien W, et al. Among authors: poellinger l. Oncotarget. 2014 Jul 15;5(13):4881-94. doi: 10.18632/oncotarget.2051. Oncotarget. 2014. PMID: 24952679 Free PMC article.

3

PIAS4 is an activator of hypoxia signalling via VHL suppression during growth of pancreatic cancer cells.

Chien W, Lee KL, Ding LW, Wuensche P, Kato H, Doan NB, Poellinger L, Said JW, Koeffler HP. Chien W, et al. Among authors: poellinger l. Br J Cancer. 2013 Oct 1;109(7):1795-804. doi: 10.1038/bjc.2013.531. Epub 2013 Sep 3. Br J Cancer. 2013. PMID: 24002598 Free PMC article.

4

Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells.

Han J, Li J, Ho JC, Chia GS, Kato H, Jha S, Yang H, Poellinger L, Lee KL. Han J, et al. Among authors: poellinger l. Sci Rep. 2017 Jun 22;7(1):4108. doi: 10.1038/s41598-017-04333-0. Sci Rep. 2017. PMID: 28642487 Free PMC article.

5

The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth.

Ueda J, Ho JC, Lee KL, Kitajima S, Yang H, Sun W, Fukuhara N, Zaiden N, Chan SL, Tachibana M, Shinkai Y, Kato H, Poellinger L. Ueda J, et al. Among authors: poellinger l. Mol Cell Biol. 2014 Oct 1;34(19):3702-20. doi: 10.1128/MCB.00099-14. Epub 2014 Jul 28. Mol Cell Biol. 2014. PMID: 25071150 Free PMC article.

6

Generating specificity and diversity in the transcriptional response to hypoxia.

Lendahl U, Lee KL, Yang H, Poellinger L. Lendahl U, et al. Among authors: poellinger l. Nat Rev Genet. 2009 Dec;10(12):821-32. doi: 10.1038/nrg2665. Epub 2009 Nov 3. Nat Rev Genet. 2009. PMID: 19884889 Review.

7

Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions.

Lee KL, Lim SK, Orlov YL, Yit le Y, Yang H, Ang LT, Poellinger L, Lim B. Lee KL, et al. Among authors: poellinger l. PLoS Genet. 2011 Jun;7(6):e1002130. doi: 10.1371/journal.pgen.1002130. Epub 2011 Jun 23. PLoS Genet. 2011. PMID: 21731500 Free PMC article.

8

Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway.

Ho JC, Abdullah LN, Pang QY, Jha S, Chow EK, Yang H, Kato H, Poellinger L, Ueda J, Lee KL. Ho JC, et al. Among authors: poellinger l. PLoS One. 2017 Nov 16;12(11):e0188051. doi: 10.1371/journal.pone.0188051. eCollection 2017. PLoS One. 2017. PMID: 29145444 Free PMC article.

9

A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition.

Kitajima S, Sun W, Lee KL, Ho JC, Oyadomari S, Okamoto T, Masai H, Poellinger L, Kato H. Kitajima S, et al. Among authors: poellinger l. Sci Rep. 2021 Feb 25;11(1):4538. doi: 10.1038/s41598-021-83857-y. Sci Rep. 2021. PMID: 33633164 Free PMC article.

10

Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition.

Ng KP, Manjeri A, Lee KL, Huang W, Tan SY, Chuah CT, Poellinger L, Ong ST. Ng KP, et al. Among authors: poellinger l. Blood. 2014 May 22;123(21):3316-26. doi: 10.1182/blood-2013-07-511907. Epub 2014 Apr 4. Blood. 2014. PMID: 24705490 Free article.

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