Yen Y - Search Results

1

Non-enzymatic action of RRM1 protein upregulates PTEN leading to inhibition of colorectal cancer metastasis.

Qi H, Lou M, Chen Y, Liu X, Chen N, Shan J, Ling Z, Shen J, Zhu L, Yen Y, Zheng S, Shao J. Qi H, et al. Among authors: yen y. Tumour Biol. 2015 Jun;36(6):4833-42. doi: 10.1007/s13277-015-3137-4. Epub 2015 Feb 1. Tumour Biol. 2015. PMID: 25638032

2

Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits.

Xue L, Zhou B, Liu X, Qiu W, Jin Z, Yen Y. Xue L, et al. Among authors: yen y. Cancer Res. 2003 Mar 1;63(5):980-6. Cancer Res. 2003. PMID: 12615712

3

In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase.

Shao J, Zhou B, Zhu L, Qiu W, Yuan YC, Xi B, Yen Y. Shao J, et al. Among authors: yen y. Cancer Res. 2004 Jan 1;64(1):1-6. doi: 10.1158/0008-5472.can-03-3048. Cancer Res. 2004. PMID: 14729598

4

Nuclear factor Y regulation and promoter transactivation of human ribonucleotide reductase subunit M2 gene in a Gemcitabine resistant KB clone.

Liu X, Zhou B, Xue L, Qiu W, Shih J, Zheng S, Yen Y. Liu X, et al. Among authors: yen y. Biochem Pharmacol. 2004 Apr 15;67(8):1499-511. doi: 10.1016/j.bcp.2003.12.026. Biochem Pharmacol. 2004. PMID: 15041467

5

Determination of the potency and subunit-selectivity of ribonucleotide reductase inhibitors with a recombinant-holoenzyme-based in vitro assay.

Shao J, Zhou B, Zhu L, Bilio AJ, Su L, Yuan YC, Ren S, Lien EJ, Shih J, Yen Y. Shao J, et al. Among authors: yen y. Biochem Pharmacol. 2005 Feb 15;69(4):627-34. doi: 10.1016/j.bcp.2004.11.016. Epub 2005 Jan 8. Biochem Pharmacol. 2005. PMID: 15670581

6

Fibroblast growth factor receptor 3 inhibition by short hairpin RNAs leads to apoptosis in multiple myeloma.

Zhu L, Somlo G, Zhou B, Shao J, Bedell V, Slovak ML, Liu X, Luo J, Yen Y. Zhu L, et al. Among authors: yen y. Mol Cancer Ther. 2005 May;4(5):787-98. doi: 10.1158/1535-7163.MCT-04-0330. Mol Cancer Ther. 2005. PMID: 15897243

7

Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits.

Qiu W, Zhou B, Darwish D, Shao J, Yen Y. Qiu W, et al. Among authors: yen y. Biochem Biophys Res Commun. 2006 Feb 10;340(2):428-34. doi: 10.1016/j.bbrc.2005.12.019. Epub 2005 Dec 15. Biochem Biophys Res Commun. 2006. PMID: 16376858

8

A Ferrous-Triapine complex mediates formation of reactive oxygen species that inactivate human ribonucleotide reductase.

Shao J, Zhou B, Di Bilio AJ, Zhu L, Wang T, Qi C, Shih J, Yen Y. Shao J, et al. Among authors: yen y. Mol Cancer Ther. 2006 Mar;5(3):586-92. doi: 10.1158/1535-7163.MCT-05-0384. Mol Cancer Ther. 2006. PMID: 16546972

9

Ribonucleotide reductase inhibitors and future drug design.

Shao J, Zhou B, Chu B, Yen Y. Shao J, et al. Among authors: yen y. Curr Cancer Drug Targets. 2006 Aug;6(5):409-31. doi: 10.2174/156800906777723949. Curr Cancer Drug Targets. 2006. PMID: 16918309 Review.

10

Metastasis-suppressing potential of ribonucleotide reductase small subunit p53R2 in human cancer cells.

Liu X, Zhou B, Xue L, Shih J, Tye K, Lin W, Qi C, Chu P, Un F, Wen W, Yen Y. Liu X, et al. Among authors: yen y. Clin Cancer Res. 2006 Nov 1;12(21):6337-44. doi: 10.1158/1078-0432.CCR-06-0799. Clin Cancer Res. 2006. PMID: 17085643

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