Wipf P - Search Results

1

Heat shock protein responses to aging and proteotoxicity in the olfactory bulb.

Crum TS, Gleixner AM, Posimo JM, Mason DM, Broeren MT, Heinemann SD, Wipf P, Brodsky JL, Leak RK. Crum TS, et al. Among authors: wipf p. J Neurochem. 2015 Jun;133(6):780-794. doi: 10.1111/jnc.13041. Epub 2015 Mar 5. J Neurochem. 2015. PMID: 25640060 Free PMC article.

2

Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity.

Fewell SW, Smith CM, Lyon MA, Dumitrescu TP, Wipf P, Day BW, Brodsky JL. Fewell SW, et al. Among authors: wipf p. J Biol Chem. 2004 Dec 3;279(49):51131-40. doi: 10.1074/jbc.M404857200. Epub 2004 Sep 23. J Biol Chem. 2004. PMID: 15448148 Free article.

3

Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer.

Rodina A, Vilenchik M, Moulick K, Aguirre J, Kim J, Chiang A, Litz J, Clement CC, Kang Y, She Y, Wu N, Felts S, Wipf P, Massague J, Jiang X, Brodsky JL, Krystal GW, Chiosis G. Rodina A, et al. Among authors: wipf p. Nat Chem Biol. 2007 Aug;3(8):498-507. doi: 10.1038/nchembio.2007.10. Epub 2007 Jul 1. Nat Chem Biol. 2007. PMID: 17603540

4

Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation.

Wright CM, Chovatiya RJ, Jameson NE, Turner DM, Zhu G, Werner S, Huryn DM, Pipas JM, Day BW, Wipf P, Brodsky JL. Wright CM, et al. Among authors: wipf p. Bioorg Med Chem. 2008 Mar 15;16(6):3291-301. doi: 10.1016/j.bmc.2007.12.014. Epub 2007 Dec 14. Bioorg Med Chem. 2008. PMID: 18164205 Free PMC article.

5

A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum.

Rabu C, Wipf P, Brodsky JL, High S. Rabu C, et al. Among authors: wipf p. J Biol Chem. 2008 Oct 10;283(41):27504-27513. doi: 10.1074/jbc.M804591200. Epub 2008 Jul 29. J Biol Chem. 2008. PMID: 18667436 Free PMC article.

6

Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum.

Chiang AN, Valderramos JC, Balachandran R, Chovatiya RJ, Mead BP, Schneider C, Bell SL, Klein MG, Huryn DM, Chen XS, Day BW, Fidock DA, Wipf P, Brodsky JL. Chiang AN, et al. Among authors: wipf p. Bioorg Med Chem. 2009 Feb 15;17(4):1527-33. doi: 10.1016/j.bmc.2009.01.024. Epub 2009 Jan 20. Bioorg Med Chem. 2009. PMID: 19195901 Free PMC article.

7

Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities.

Patham B, Duffy J, Lane A, Davis RC, Wipf P, Fewell SW, Brodsky JL, Mensa-Wilmot K. Patham B, et al. Among authors: wipf p. Biochem J. 2009 Apr 15;419(2):507-17. doi: 10.1042/BJ20081787. Biochem J. 2009. PMID: 19196237 Free PMC article.

8

Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen.

Wright CM, Seguin SP, Fewell SW, Zhang H, Ishwad C, Vats A, Lingwood CA, Wipf P, Fanning E, Pipas JM, Brodsky JL. Wright CM, et al. Among authors: wipf p. Virus Res. 2009 Apr;141(1):71-80. doi: 10.1016/j.virusres.2008.12.018. Epub 2009 Feb 4. Virus Res. 2009. PMID: 19200446 Free PMC article.

9

Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.

Wisén S, Bertelsen EB, Thompson AD, Patury S, Ung P, Chang L, Evans CG, Walter GM, Wipf P, Carlson HA, Brodsky JL, Zuiderweg ER, Gestwicki JE. Wisén S, et al. Among authors: wipf p. ACS Chem Biol. 2010 Jun 18;5(6):611-22. doi: 10.1021/cb1000422. ACS Chem Biol. 2010. PMID: 20481474 Free PMC article.

10

Plasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shock.

Botha M, Chiang AN, Needham PG, Stephens LL, Hoppe HC, Külzer S, Przyborski JM, Lingelbach K, Wipf P, Brodsky JL, Shonhai A, Blatch GL. Botha M, et al. Among authors: wipf p. Cell Stress Chaperones. 2011 Jul;16(4):389-401. doi: 10.1007/s12192-010-0250-6. Epub 2010 Dec 30. Cell Stress Chaperones. 2011. PMID: 21191678 Free PMC article.

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