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Page 1
Humanized medium (h7H) allows long-term primary follicular thyroid cultures from human normal thyroid, benign neoplasm, and cancer.
Bravo SB, Garcia-Rendueles ME, Garcia-Rendueles AR, Rodrigues JS, Perez-Romero S, Garcia-Lavandeira M, Suarez-Fariña M, Barreiro F, Czarnocka B, Senra A, Lareu MV, Rodriguez-Garcia J, Cameselle-Teijeiro J, Alvarez CV. Bravo SB, et al. Among authors: garcia rendueles ar. J Clin Endocrinol Metab. 2013 Jun;98(6):2431-41. doi: 10.1210/jc.2012-3812. Epub 2013 Mar 28. J Clin Endocrinol Metab. 2013. PMID: 23539720
Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF.
Diaz-Rodriguez E, Garcia-Rendueles AR, Ibáñez-Costa A, Gutierrez-Pascual E, Garcia-Lavandeira M, Leal A, Japon MA, Soto A, Venegas E, Tinahones FJ, Garcia-Arnes JA, Benito P, Angeles Galvez M, Jimenez-Reina L, Bernabeu I, Dieguez C, Luque RM, Castaño JP, Alvarez CV. Diaz-Rodriguez E, et al. Among authors: garcia rendueles ar. Endocrinology. 2014 Nov;155(11):4329-40. doi: 10.1210/en.2014-1034. Epub 2014 Aug 19. Endocrinology. 2014. PMID: 25137025
Rewiring of the apoptotic TGF-β-SMAD/NFκB pathway through an oncogenic function of p27 in human papillary thyroid cancer.
Garcia-Rendueles AR, Rodrigues JS, Garcia-Rendueles ME, Suarez-Fariña M, Perez-Romero S, Barreiro F, Bernabeu I, Rodriguez-Garcia J, Fugazzola L, Sakai T, Liu F, Cameselle-Teijeiro J, Bravo SB, Alvarez CV. Garcia-Rendueles AR, et al. Oncogene. 2017 Feb 2;36(5):652-666. doi: 10.1038/onc.2016.233. Epub 2016 Jul 25. Oncogene. 2017. PMID: 27452523
The syndrome of central hypothyroidism and macroorchidism: IGSF1 controls TRHR and FSHB expression by differential modulation of pituitary TGFβ and Activin pathways.
García M, Barrio R, García-Lavandeira M, Garcia-Rendueles AR, Escudero A, Díaz-Rodríguez E, Gorbenko Del Blanco D, Fernández A, de Rijke YB, Vallespín E, Nevado J, Lapunzina P, Matre V, Hinkle PM, Hokken-Koelega AC, de Miguel MP, Cameselle-Teijeiro JM, Nistal M, Alvarez CV, Moreno JC. García M, et al. Among authors: garcia rendueles ar. Sci Rep. 2017 Mar 6;7:42937. doi: 10.1038/srep42937. Sci Rep. 2017. PMID: 28262687 Free PMC article.
Unmasking a new prognostic marker and therapeutic target from the GDNF-RET/PIT1/p14ARF/p53 pathway in acromegaly.
Chenlo M, Rodriguez-Gomez IA, Serramito R, Garcia-Rendueles AR, Villar-Taibo R, Fernandez-Rodriguez E, Perez-Romero S, Suarez-Fariña M, Garcia-Allut A, Cabezas-Agricola JM, Rodriguez-Garcia J, Lear PV, Alvarez-San Martin RM, Alvarez-Escola C, Bernabeu I, Alvarez CV. Chenlo M, et al. Among authors: garcia rendueles ar. EBioMedicine. 2019 May;43:537-552. doi: 10.1016/j.ebiom.2019.04.007. Epub 2019 Apr 8. EBioMedicine. 2019. PMID: 30975543 Free PMC article.
GFRα 1-2-3-4 co-receptors for RET Are co-expressed in Pituitary Stem Cells but Individually Retained in Some Adenopituitary Cells.
Pradilla Dieste A, Chenlo M, Perez-Romero S, Garcia-Rendueles ÁR, Suarez-Fariña M, Garcia-Lavandeira M, Bernabeu I, Cameselle-Teijeiro JM, Alvarez CV. Pradilla Dieste A, et al. Among authors: garcia rendueles ar. Front Endocrinol (Lausanne). 2020 Sep 24;11:631. doi: 10.3389/fendo.2020.00631. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33071961 Free PMC article.
Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis.
Gómez-Valadés AG, Pozo M, Varela L, Boudjadja MB, Ramírez S, Chivite I, Eyre E, Haddad-Tóvolli R, Obri A, Milà-Guasch M, Altirriba J, Schneeberger M, Imbernón M, Garcia-Rendueles AR, Gama-Perez P, Rojo-Ruiz J, Rácz B, Alonso MT, Gomis R, Zorzano A, D'Agostino G, Alvarez CV, Nogueiras R, Garcia-Roves PM, Horvath TL, Claret M. Gómez-Valadés AG, et al. Among authors: garcia rendueles ar. Cell Metab. 2021 Sep 7;33(9):1820-1835.e9. doi: 10.1016/j.cmet.2021.07.008. Epub 2021 Aug 2. Cell Metab. 2021. PMID: 34343501 Free PMC article.
RET signalling provides tumorigenic mechanism and tissue specificity for AIP-related somatotrophinomas.
Garcia-Rendueles AR, Chenlo M, Oroz-Gonjar F, Solomou A, Mistry A, Barry S, Gaston-Massuet C, Garcia-Lavandeira M, Perez-Romero S, Suarez-Fariña M, Pradilla-Dieste A, Dieguez C, Mehlen P, Korbonits M, Alvarez CV. Garcia-Rendueles AR, et al. Oncogene. 2021 Nov;40(45):6354-6368. doi: 10.1038/s41388-021-02009-8. Epub 2021 Sep 29. Oncogene. 2021. PMID: 34588620 Free PMC article.
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