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A Big Bang model of human colorectal tumor growth.
Sottoriva A, Kang H, Ma Z, Graham TA, Salomon MP, Zhao J, Marjoram P, Siegmund K, Press MF, Shibata D, Curtis C. Sottoriva A, et al. Among authors: siegmund k. Nat Genet. 2015 Mar;47(3):209-16. doi: 10.1038/ng.3214. Epub 2015 Feb 9. Nat Genet. 2015. PMID: 25665006 Free PMC article.
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.
Weisenberger DJ, Siegmund KD, Campan M, Young J, Long TI, Faasse MA, Kang GH, Widschwendter M, Weener D, Buchanan D, Koh H, Simms L, Barker M, Leggett B, Levine J, Kim M, French AJ, Thibodeau SN, Jass J, Haile R, Laird PW. Weisenberger DJ, et al. Nat Genet. 2006 Jul;38(7):787-93. doi: 10.1038/ng1834. Epub 2006 Jun 25. Nat Genet. 2006. PMID: 16804544
Modeling DNA methylation in a population of cancer cells.
Siegmund KD, Marjoram P, Shibata D. Siegmund KD, et al. Stat Appl Genet Mol Biol. 2008;7(1):Article 18. doi: 10.2202/1544-6115.1374. Epub 2008 Jun 22. Stat Appl Genet Mol Biol. 2008. PMID: 18597664
223 results