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Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection.
Xu HC, Huang J, Khairnar V, Duhan V, Pandyra AA, Grusdat M, Shinde P, McIlwain DR, Maney SK, Gommerman J, Löhning M, Ohashi PS, Mak TW, Pieper K, Sic H, Speletas M, Eibel H, Ware CF, Tumanov AV, Kruglov AA, Nedospasov SA, Häussinger D, Recher M, Lang KS, Lang PA. Xu HC, et al. Among authors: haussinger d. J Virol. 2015 May;89(9):4748-59. doi: 10.1128/JVI.02976-14. Epub 2015 Feb 11. J Virol. 2015. PMID: 25673724 Free PMC article.
Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice.
Lang PA, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, Cervantes-Barragan L, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, Häussinger D, Ohashi PS, Zinkernagel RM, Lang KS. Lang PA, et al. Among authors: haussinger d. Hepatology. 2010 Jul;52(1):25-32. doi: 10.1002/hep.23640. Hepatology. 2010. PMID: 20578253
Oxidized ATP inhibits T-cell-mediated autoimmunity.
Lang PA, Merkler D, Funkner P, Shaabani N, Meryk A, Krings C, Barthuber C, Recher M, Brück W, Häussinger D, Ohashi PS, Lang KS. Lang PA, et al. Among authors: haussinger d. Eur J Immunol. 2010 Sep;40(9):2401-8. doi: 10.1002/eji.200939838. Eur J Immunol. 2010. PMID: 20683833 Free article.
Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulatory effects of MK3.
Ehlting C, Ronkina N, Böhmer O, Albrecht U, Bode KA, Lang KS, Kotlyarov A, Radzioch D, Gaestel M, Häussinger D, Bode JG. Ehlting C, et al. Among authors: haussinger d. J Biol Chem. 2011 Jul 8;286(27):24113-24. doi: 10.1074/jbc.M111.235275. Epub 2011 May 17. J Biol Chem. 2011. PMID: 21586572 Free PMC article.
Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus.
Honke N, Shaabani N, Cadeddu G, Sorg UR, Zhang DE, Trilling M, Klingel K, Sauter M, Kandolf R, Gailus N, van Rooijen N, Burkart C, Baldus SE, Grusdat M, Löhning M, Hengel H, Pfeffer K, Tanaka M, Häussinger D, Recher M, Lang PA, Lang KS. Honke N, et al. Among authors: haussinger d. Nat Immunol. 2011 Nov 20;13(1):51-7. doi: 10.1038/ni.2169. Nat Immunol. 2011. PMID: 22101728
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity.
Lang PA, Lang KS, Xu HC, Grusdat M, Parish IA, Recher M, Elford AR, Dhanji S, Shaabani N, Tran CW, Dissanayake D, Rahbar R, Ghazarian M, Brüstle A, Fine J, Chen P, Weaver CT, Klose C, Diefenbach A, Häussinger D, Carlyle JR, Kaech SM, Mak TW, Ohashi PS. Lang PA, et al. Among authors: haussinger d. Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1210-5. doi: 10.1073/pnas.1118834109. Epub 2011 Dec 13. Proc Natl Acad Sci U S A. 2012. PMID: 22167808 Free PMC article.
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.
McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, Ohashi PS, Blobel CP, Mak TW. McIlwain DR, et al. Among authors: haussinger d. Science. 2012 Jan 13;335(6065):229-32. doi: 10.1126/science.1214448. Science. 2012. PMID: 22246778 Free PMC article.
Tunicamycin inhibits diabetes.
Shaabani N, Honke N, Lang PA, Görg B, Proksch P, Gailus N, Gotoh T, Häussinger D, Lang KS. Shaabani N, et al. Among authors: haussinger d. Cell Physiol Biochem. 2012;29(3-4):595-602. doi: 10.1159/000338513. Epub 2012 Apr 3. Cell Physiol Biochem. 2012. PMID: 22508066
1,112 results