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Targeting a cell state common to triple-negative breast cancers.
Muellner MK, Mair B, Ibrahim Y, Kerzendorfer C, Lechtermann H, Trefzer C, Klepsch F, Müller AC, Leitner E, Macho-Maschler S, Superti-Furga G, Bennett KL, Baselga J, Rix U, Kubicek S, Colinge J, Serra V, Nijman SM. Muellner MK, et al. Mol Syst Biol. 2015 Feb 19;11(1):789. doi: 10.15252/msb.20145664. Mol Syst Biol. 2015. PMID: 25699542 Free PMC article.
Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade.
Woess K, Macho-Maschler S, Van Ingen Schenau DS, Butler M, Lassnig C, Valcanover D, Poelzl A, Meissl K, Maurer B, Brandstoetter T, Vogl C, Koren A, Kubicek S, Orlova A, Moriggl R, Strobl B, Sexl V, Van Leeuwen FN, Kuiper RP, Mueller M. Woess K, et al. Among authors: macho maschler s. Haematologica. 2023 Apr 1;108(4):993-1005. doi: 10.3324/haematol.2021.279848. Haematologica. 2023. PMID: 35021603 Free PMC article.
TYK2 in Tumor Immunosurveillance.
Karjalainen A, Shoebridge S, Krunic M, Simonović N, Tebb G, Macho-Maschler S, Strobl B, Müller M. Karjalainen A, et al. Among authors: macho maschler s. Cancers (Basel). 2020 Jan 8;12(1):150. doi: 10.3390/cancers12010150. Cancers (Basel). 2020. PMID: 31936322 Free PMC article. Review.
TYK2: An Upstream Kinase of STATs in Cancer.
Wöss K, Simonović N, Strobl B, Macho-Maschler S, Müller M. Wöss K, et al. Among authors: macho maschler s. Cancers (Basel). 2019 Nov 5;11(11):1728. doi: 10.3390/cancers11111728. Cancers (Basel). 2019. PMID: 31694222 Free PMC article. Review.
Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.
Gawish R, Bulat T, Biaggio M, Lassnig C, Bago-Horvath Z, Macho-Maschler S, Poelzl A, Simonović N, Prchal-Murphy M, Rom R, Amenitsch L, Ferrarese L, Kornhoff J, Lederer T, Svinka J, Eferl R, Bosmann M, Kalinke U, Stoiber D, Sexl V, Krmpotić A, Jonjić S, Müller M, Strobl B. Gawish R, et al. Among authors: macho maschler s. Cell Rep. 2019 Feb 26;26(9):2394-2406.e5. doi: 10.1016/j.celrep.2019.02.017. Cell Rep. 2019. PMID: 30811989 Free PMC article.
The good and the bad faces of STAT1 in solid tumours.
Meissl K, Macho-Maschler S, Müller M, Strobl B. Meissl K, et al. Among authors: macho maschler s. Cytokine. 2017 Jan;89:12-20. doi: 10.1016/j.cyto.2015.11.011. Epub 2015 Nov 26. Cytokine. 2017. PMID: 26631912 Free article. Review.
Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen-urokinase plasminogen activator receptor system-regulated secretion during breast cancer progression.
Csiszar A, Kutay B, Wirth S, Schmidt U, Macho-Maschler S, Schreiber M, Alacakaptan M, Vogel GF, Aumayr K, Huber LA, Beug H. Csiszar A, et al. Breast Cancer Res. 2014 Sep 9;16(5):433. doi: 10.1186/s13058-014-0433-7. Breast Cancer Res. 2014. PMID: 25212966 Free PMC article.
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