Jude KM - Search Results

1

Structural biology. Structural basis for Notch1 engagement of Delta-like 4.

Luca VC, Jude KM, Pierce NW, Nachury MV, Fischer S, Garcia KC. Luca VC, et al. Among authors: jude km. Science. 2015 Feb 20;347(6224):847-53. doi: 10.1126/science.1261093. Science. 2015. PMID: 25700513 Free PMC article.

2

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor.

Burg JS, Ingram JR, Venkatakrishnan AJ, Jude KM, Dukkipati A, Feinberg EN, Angelini A, Waghray D, Dror RO, Ploegh HL, Garcia KC. Burg JS, et al. Among authors: jude km. Science. 2015 Mar 6;347(6226):1113-7. doi: 10.1126/science.aaa5026. Science. 2015. PMID: 25745166 Free PMC article.

3

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.

Spangler JB, Tomala J, Luca VC, Jude KM, Dong S, Ring AM, Votavova P, Pepper M, Kovar M, Garcia KC. Spangler JB, et al. Among authors: jude km. Immunity. 2015 May 19;42(5):815-25. doi: 10.1016/j.immuni.2015.04.015. Immunity. 2015. PMID: 25992858 Free PMC article.

4

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.

Moraga I, Richter D, Wilmes S, Winkelmann H, Jude K, Thomas C, Suhoski MM, Engleman EG, Piehler J, Garcia KC. Moraga I, et al. Sci Signal. 2015 Nov 10;8(402):ra114. doi: 10.1126/scisignal.aab2677. Sci Signal. 2015. PMID: 26554818 Free PMC article.

5

The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity.

Mendoza JL, Schneider WM, Hoffmann HH, Vercauteren K, Jude KM, Xiong A, Moraga I, Horton TM, Glenn JS, de Jong YP, Rice CM, Garcia KC. Mendoza JL, et al. Among authors: jude km. Immunity. 2017 Mar 21;46(3):379-392. doi: 10.1016/j.immuni.2017.02.017. Immunity. 2017. PMID: 28329704 Free PMC article.

6

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes.

Sockolosky JT, Trotta E, Parisi G, Picton L, Su LL, Le AC, Chhabra A, Silveria SL, George BM, King IC, Tiffany MR, Jude K, Sibener LV, Baker D, Shizuru JA, Ribas A, Bluestone JA, Garcia KC. Sockolosky JT, et al. Science. 2018 Mar 2;359(6379):1037-1042. doi: 10.1126/science.aar3246. Science. 2018. PMID: 29496879 Free PMC article.

7

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.

Miles TF, Spiess K, Jude KM, Tsutsumi N, Burg JS, Ingram JR, Waghray D, Hjorto GM, Larsen O, Ploegh HL, Rosenkilde MM, Garcia KC. Miles TF, et al. Among authors: jude km. Elife. 2018 Jun 8;7:e35850. doi: 10.7554/eLife.35850. Elife. 2018. PMID: 29882741 Free PMC article.

8

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism.

Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL, Garcia KC, Crellin NK, Rondon IJ, Bluestone JA. Trotta E, et al. Among authors: jude km. Nat Med. 2018 Jul;24(7):1005-1014. doi: 10.1038/s41591-018-0070-2. Epub 2018 Jun 25. Nat Med. 2018. PMID: 29942088 Free PMC article.

9

Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.

Gee MH, Sibener LV, Birnbaum ME, Jude KM, Yang X, Fernandes RA, Mendoza JL, Glassman CR, Garcia KC. Gee MH, et al. Among authors: jude km. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7369-E7378. doi: 10.1073/pnas.1802746115. Epub 2018 Jul 18. Proc Natl Acad Sci U S A. 2018. PMID: 30021852 Free PMC article.

10

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.

Sibener LV, Fernandes RA, Kolawole EM, Carbone CB, Liu F, McAffee D, Birnbaum ME, Yang X, Su LF, Yu W, Dong S, Gee MH, Jude KM, Davis MM, Groves JT, Goddard WA 3rd, Heath JR, Evavold BD, Vale RD, Garcia KC. Sibener LV, et al. Among authors: jude km. Cell. 2018 Jul 26;174(3):672-687.e27. doi: 10.1016/j.cell.2018.06.017. Cell. 2018. PMID: 30053426 Free PMC article.

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