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Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression.
Tan Y, Tajik A, Chen J, Jia Q, Chowdhury F, Wang L, Chen J, Zhang S, Hong Y, Yi H, Wu DC, Zhang Y, Wei F, Poh YC, Seong J, Singh R, Lin LJ, Doğanay S, Li Y, Jia H, Ha T, Wang Y, Huang B, Wang N. Tan Y, et al. Among authors: wang l, wang y, wang n. Nat Commun. 2014 Aug 6;5:4619. doi: 10.1038/ncomms5619. Nat Commun. 2014. PMID: 25099074 Free PMC article.
Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles.
Ma J, Zhang Y, Tang K, Zhang H, Yin X, Li Y, Xu P, Sun Y, Ma R, Ji T, Chen J, Zhang S, Zhang T, Luo S, Jin Y, Luo X, Li C, Gong H, Long Z, Lu J, Hu Z, Cao X, Wang N, Yang X, Huang B. Ma J, et al. Among authors: wang n. Cell Res. 2016 Jun;26(6):713-27. doi: 10.1038/cr.2016.53. Epub 2016 May 10. Cell Res. 2016. PMID: 27167569 Free PMC article. Clinical Trial.
Soft matrices downregulate FAK activity to promote growth of tumor-repopulating cells.
Tan Y, Wood AR, Jia Q, Zhou W, Luo J, Yang F, Chen J, Chen J, Sun J, Seong J, Tajik A, Singh R, Wang N. Tan Y, et al. Among authors: wang n. Biochem Biophys Res Commun. 2017 Jan 29;483(1):456-462. doi: 10.1016/j.bbrc.2016.12.122. Epub 2016 Dec 20. Biochem Biophys Res Commun. 2017. PMID: 28007596 Free PMC article.
Inhibition of cancer stem cell like cells by a synthetic retinoid.
Chen J, Cao X, An Q, Zhang Y, Li K, Yao W, Shi F, Pan Y, Jia Q, Zhou W, Yang F, Wei F, Wang N, Yu B. Chen J, et al. Among authors: wang n. Nat Commun. 2018 Apr 11;9(1):1406. doi: 10.1038/s41467-018-03877-7. Nat Commun. 2018. PMID: 29643385 Free PMC article.
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