Carroll SS - Search Results

1

P2-quinazolinones and bis-macrocycles as new templates for next-generation hepatitis C virus NS3/4a protease inhibitors: discovery of MK-2748 and MK-6325.

Rudd MT, Butcher JW, Nguyen KT, McIntyre CJ, Romano JJ, Gilbert KF, Bush KJ, Liverton NJ, Holloway MK, Harper S, Ferrara M, DiFilippo M, Summa V, Swestock J, Fritzen J, Carroll SS, Burlein C, DiMuzio JM, Gates A, Graham DJ, Huang Q, McClain S, McHale C, Stahlhut MW, Black S, Chase R, Soriano A, Fandozzi CM, Taylor A, Trainor N, Olsen DB, Coleman PJ, Ludmerer SW, McCauley JA. Rudd MT, et al. Among authors: carroll ss. ChemMedChem. 2015 Apr;10(4):727-35. doi: 10.1002/cmdc.201402558. Epub 2015 Mar 10. ChemMedChem. 2015. PMID: 25759009

2

Sensitivity of HIV-1 reverse transcriptase and its mutants to inhibition by azidothymidine triphosphate.

Carroll SS, Geib J, Olsen DB, Stahlhut M, Shafer JA, Kuo LC. Carroll SS, et al. Biochemistry. 1994 Mar 1;33(8):2113-20. doi: 10.1021/bi00174a018. Biochemistry. 1994. PMID: 7509634

3

Effect of template secondary structure on the inhibition of HIV-1 reverse transcriptase by a pyridinone non-nucleoside inhibitor.

Olsen DB, Carroll SS, Culberson JC, Shafer JA, Kuo LC. Olsen DB, et al. Among authors: carroll ss. Nucleic Acids Res. 1994 Apr 25;22(8):1437-43. doi: 10.1093/nar/22.8.1437. Nucleic Acids Res. 1994. PMID: 7514786 Free PMC article.

4

Inhibition of HIV-1 reverse transcriptase by a quinazolinone and comparison with inhibition by pyridinones. Differences in the rates of inhibitor binding and in synergistic inhibition with nucleoside analogs.

Carroll SS, Stahlhut M, Geib J, Olsen DB. Carroll SS, et al. J Biol Chem. 1994 Dec 23;269(51):32351-7. J Biol Chem. 1994. PMID: 7528214 Free article.

5

Inhibition of HIV-1 reverse transcriptase by pyridinone derivatives. Potency, binding characteristics, and effect of template sequence.

Carroll SS, Olsen DB, Bennett CD, Gotlib L, Graham DJ, Condra JH, Stern AM, Shafer JA, Kuo LC. Carroll SS, et al. J Biol Chem. 1993 Jan 5;268(1):276-81. J Biol Chem. 1993. PMID: 7677997 Free article.

6

L-743, 726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase.

Young SD, Britcher SF, Tran LO, Payne LS, Lumma WC, Lyle TA, Huff JR, Anderson PS, Olsen DB, Carroll SS, et al. Young SD, et al. Among authors: carroll ss. Antimicrob Agents Chemother. 1995 Dec;39(12):2602-5. doi: 10.1128/AAC.39.12.2602. Antimicrob Agents Chemother. 1995. PMID: 8592986 Free PMC article.

7

Preparation and use of synthetic oligoribonucleotides as tools for study of viral polymerases.

Carroll SS, Benseler F, Olsen DB. Carroll SS, et al. Methods Enzymol. 1996;275:365-82. doi: 10.1016/s0076-6879(96)75022-x. Methods Enzymol. 1996. PMID: 9026650 No abstract available.

8

Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino)thien-2-yl]-2,4-dioxobutanoic acid.

Shaw-Reid CA, Munshi V, Graham P, Wolfe A, Witmer M, Danzeisen R, Olsen DB, Carroll SS, Embrey M, Wai JS, Miller MD, Cole JL, Hazuda DJ. Shaw-Reid CA, et al. Among authors: carroll ss. J Biol Chem. 2003 Jan 31;278(5):2777-80. doi: 10.1074/jbc.C200621200. Epub 2002 Dec 11. J Biol Chem. 2003. PMID: 12480948 Free article.

9

Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs.

Carroll SS, Tomassini JE, Bosserman M, Getty K, Stahlhut MW, Eldrup AB, Bhat B, Hall D, Simcoe AL, LaFemina R, Rutkowski CA, Wolanski B, Yang Z, Migliaccio G, De Francesco R, Kuo LC, MacCoss M, Olsen DB. Carroll SS, et al. J Biol Chem. 2003 Apr 4;278(14):11979-84. doi: 10.1074/jbc.M210914200. Epub 2003 Jan 27. J Biol Chem. 2003. PMID: 12554735 Free article.

10

Electrochemiluminescence assay for basic carboxypeptidases: inhibition of basic carboxypeptidases and activation of thrombin-activatable fibrinolysis inhibitor.

Mao SS, Colussi D, Bailey CM, Bosserman M, Burlein C, Gardell SJ, Carroll SS. Mao SS, et al. Among authors: carroll ss. Anal Biochem. 2003 Aug 1;319(1):159-70. doi: 10.1016/s0003-2697(03)00252-5. Anal Biochem. 2003. PMID: 12842119

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