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Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge.
Sholukh AM, Watkins JD, Vyas HK, Gupta S, Lakhashe SK, Thorat S, Zhou M, Hemashettar G, Bachler BC, Forthal DN, Villinger F, Sattentau QJ, Weiss RA, Agatic G, Corti D, Lanzavecchia A, Heeney JL, Ruprecht RM. Sholukh AM, et al. Among authors: gupta s. Vaccine. 2015 Apr 21;33(17):2086-95. doi: 10.1016/j.vaccine.2015.02.020. Epub 2015 Mar 11. Vaccine. 2015. PMID: 25769884 Free PMC article.
Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission.
Watkins JD, Sholukh AM, Mukhtar MM, Siddappa NB, Lakhashe SK, Kim M, Reinherz EL, Gupta S, Forthal DN, Sattentau QJ, Villinger F, Corti D, Ruprecht RM; CAVD Project Group. Watkins JD, et al. Among authors: gupta s. AIDS. 2013 Jun 1;27(9):F13-20. doi: 10.1097/QAD.0b013e328360eac6. AIDS. 2013. PMID: 23775002 Free PMC article.
Novel Strategy To Adapt Simian-Human Immunodeficiency Virus E1 Carrying env from an RV144 Volunteer to Rhesus Macaques: Coreceptor Switch and Final Recovery of a Pathogenic Virus with Exclusive R5 Tropism.
Scinto HB, Gupta S, Thorat S, Mukhtar MM, Griffiths A, Delgado J, Plake E, Vyas HK, Strickland A, Byrareddy SN, Montefiori DC, LaBranche C, Pal R, Treece J, Orndorff S, Ferrari MG, Weiss D, Chenine AL, McLinden R, Michael N, Kim JH, Robb ML, Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, Ruprecht RM. Scinto HB, et al. Among authors: gupta s. J Virol. 2018 Jun 29;92(14):e02222-17. doi: 10.1128/JVI.02222-17. Print 2018 Jul 15. J Virol. 2018. PMID: 29743361 Free PMC article.
The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells.
Gupta S, Gach JS, Becerra JC, Phan TB, Pudney J, Moldoveanu Z, Joseph SB, Landucci G, Supnet MJ, Ping LH, Corti D, Moldt B, Hel Z, Lanzavecchia A, Ruprecht RM, Burton DR, Mestecky J, Anderson DJ, Forthal DN. Gupta S, et al. PLoS Pathog. 2013;9(11):e1003776. doi: 10.1371/journal.ppat.1003776. Epub 2013 Nov 21. PLoS Pathog. 2013. PMID: 24278022 Free PMC article. Clinical Trial.
Localization of infection in neonatal rhesus macaques after oral viral challenge.
Taylor RA, McRaven MD, Carias AM, Anderson MR, Matias E, Araínga M, Allen EJ, Rogers KA, Gupta S, Kulkarni V, Lakhashe S, Lorenzo-Redondo R, Thomas Y, Strickland A, Villinger FJ, Ruprecht RM, Hope TJ. Taylor RA, et al. Among authors: gupta s. PLoS Pathog. 2021 Nov 18;17(11):e1009855. doi: 10.1371/journal.ppat.1009855. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34793582 Free PMC article.
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