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Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge.
Sholukh AM, Watkins JD, Vyas HK, Gupta S, Lakhashe SK, Thorat S, Zhou M, Hemashettar G, Bachler BC, Forthal DN, Villinger F, Sattentau QJ, Weiss RA, Agatic G, Corti D, Lanzavecchia A, Heeney JL, Ruprecht RM. Sholukh AM, et al. Among authors: villinger f. Vaccine. 2015 Apr 21;33(17):2086-95. doi: 10.1016/j.vaccine.2015.02.020. Epub 2015 Mar 11. Vaccine. 2015. PMID: 25769884 Free PMC article.
Suppression of acute viremia by short-term postexposure prophylaxis of simian/human immunodeficiency virus SHIV-RT-infected monkeys with a novel reverse transcriptase inhibitor (GW420867) allows for development of potent antiviral immune responses resulting in efficient containment of infection.
Mori K, Yasutomi Y, Sawada S, Villinger F, Sugama K, Rosenwith B, Heeney JL, Uberla K, Yamazaki S, Ansari AA, Rübsamen-Waigmann H. Mori K, et al. Among authors: villinger f. J Virol. 2000 Jul;74(13):5747-53. doi: 10.1128/jvi.74.13.5747-5753.2000. J Virol. 2000. PMID: 10846052 Free PMC article.
Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.
Amara RR, Villinger F, Altman JD, Lydy SL, O'Neil SP, Staprans SI, Montefiori DC, Xu Y, Herndon JG, Wyatt LS, Candido MA, Kozyr NL, Earl PL, Smith JM, Ma HL, Grimm BD, Hulsey ML, Miller J, McClure HM, McNicholl JM, Moss B, Robinson HL. Amara RR, et al. Among authors: villinger f. Science. 2001 Apr 6;292(5514):69-74. doi: 10.1126/science.1058915. Science. 2001. PMID: 11393868
Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.
Amara RR, Villinger F, Altman JD, Lydy SL, O'Neil SP, Staprans SI, Montefiori DC, Xu Y, Herndon JG, Wyatt LS, Candido MA, Kozyr NL, Earl PL, Smith JM, Ma HL, Grimm BD, Hulsey ML, McClure HM, McNicholl JM, Moss B, Robinson HL. Amara RR, et al. Among authors: villinger f. Vaccine. 2002 May 6;20(15):1949-55. doi: 10.1016/s0264-410x(02)00076-2. Vaccine. 2002. PMID: 11983252 Review.
GM-CSF DNA: an adjuvant for higher avidity IgG, rectal IgA, and increased protection against the acute phase of a SHIV-89.6P challenge by a DNA/MVA immunodeficiency virus vaccine.
Lai L, Vödrös D, Kozlowski PA, Montefiori DC, Wilson RL, Akerstrom VL, Chennareddi L, Yu T, Kannanganat S, Ofielu L, Villinger F, Wyatt LS, Moss B, Amara RR, Robinson HL. Lai L, et al. Among authors: villinger f. Virology. 2007 Dec 5;369(1):153-67. doi: 10.1016/j.virol.2007.07.017. Epub 2007 Aug 14. Virology. 2007. PMID: 17698160 Free PMC article.
Relative transmissibility of an R5 clade C simian-human immunodeficiency virus across different mucosae in macaques parallels the relative risks of sexual HIV-1 transmission in humans via different routes.
Chenine AL, Siddappa NB, Kramer VG, Sciaranghella G, Rasmussen RA, Lee SJ, Santosuosso M, Poznansky MC, Velu V, Amara RR, Souder C, Anderson DC, Villinger F, Else JG, Novembre FJ, Strobert E, O'Neil SP, Secor WE, Ruprecht RM. Chenine AL, et al. Among authors: villinger f. J Infect Dis. 2010 Apr 15;201(8):1155-63. doi: 10.1086/651274. J Infect Dis. 2010. PMID: 20214475 Free PMC article.
AIDS and optic neuritis in a rhesus monkey infected with the R5 clade C SHIV-1157ipd3N4.
García A, Siddappa NB, Li Q, Haase AT, Paul K, Stroud F, Zhang X, Fountain JA, Villinger F, Novembre FJ, Else JG, Evan Secor W, Ruprecht RM. García A, et al. Among authors: villinger f. J Med Primatol. 2010 Oct;39(5):356-60. doi: 10.1111/j.1600-0684.2010.00416.x. J Med Primatol. 2010. PMID: 20412378 Free PMC article.
R5 clade C SHIV strains with tier 1 or 2 neutralization sensitivity: tools to dissect env evolution and to develop AIDS vaccines in primate models.
Siddappa NB, Watkins JD, Wassermann KJ, Song R, Wang W, Kramer VG, Lakhashe S, Santosuosso M, Poznansky MC, Novembre FJ, Villinger F, Else JG, Montefiori DC, Rasmussen RA, Ruprecht RM. Siddappa NB, et al. Among authors: villinger f. PLoS One. 2010 Jul 21;5(7):e11689. doi: 10.1371/journal.pone.0011689. PLoS One. 2010. PMID: 20657739 Free PMC article.
321 results