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Page 1
Efficient total synthesis of ammosamide B.
Reddy PV, Banerjee B, Cushman M. Reddy PV, et al. Org Lett. 2010 Jul 2;12(13):3112-4. doi: 10.1021/ol101215x. Org Lett. 2010. PMID: 20515072 Free PMC article.
Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents.
Chen L, Conda-Sheridan M, Reddy PV, Morrell A, Park EJ, Kondratyuk TP, Pezzuto JM, van Breemen RB, Cushman M. Chen L, et al. Among authors: reddy pv. J Med Chem. 2012 Jun 28;55(12):5965-81. doi: 10.1021/jm3006806. Epub 2012 Jun 19. J Med Chem. 2012. PMID: 22712432 Free PMC article.
Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I poisons.
Cinelli MA, Reddy PV, Lv PC, Liang JH, Chen L, Agama K, Pommier Y, van Breemen RB, Cushman M. Cinelli MA, et al. Among authors: reddy pv. J Med Chem. 2012 Dec 27;55(24):10844-62. doi: 10.1021/jm300519w. Epub 2012 Dec 7. J Med Chem. 2012. PMID: 23215354 Free PMC article.
Synthesis and biological evaluation of indenoisoquinolines that inhibit both tyrosyl-DNA phosphodiesterase I (Tdp1) and topoisomerase I (Top1).
Conda-Sheridan M, Reddy PV, Morrell A, Cobb BT, Marchand C, Agama K, Chergui A, Renaud A, Stephen AG, Bindu LK, Pommier Y, Cushman M. Conda-Sheridan M, et al. Among authors: reddy pv. J Med Chem. 2013 Jan 10;56(1):182-200. doi: 10.1021/jm3014458. Epub 2012 Dec 21. J Med Chem. 2013. PMID: 23259865 Free PMC article.
196 results