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ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation.
Alemdehy MF, Haanstra JR, de Looper HW, van Strien PM, Verhagen-Oldenampsen J, Caljouw Y, Sanders MA, Hoogenboezem R, de Ru AH, Janssen GM, Smetsers SE, Bierings MB, van Veelen PA, von Lindern M, Touw IP, Erkeland SJ. Alemdehy MF, et al. Among authors: janssen gm. Blood. 2015 Jun 18;125(25):3937-48. doi: 10.1182/blood-2014-11-612507. Epub 2015 Mar 16. Blood. 2015. PMID: 25778535 Free article.
The redox state of transglutaminase 2 controls arterial remodeling.
van den Akker J, VanBavel E, van Geel R, Matlung HL, Guvenc Tuna B, Janssen GM, van Veelen PA, Boelens WC, De Mey JG, Bakker EN. van den Akker J, et al. Among authors: janssen gm. PLoS One. 2011;6(8):e23067. doi: 10.1371/journal.pone.0023067. Epub 2011 Aug 25. PLoS One. 2011. PMID: 21901120 Free PMC article.
Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire.
van Lummel M, van Veelen PA, Zaldumbide A, de Ru A, Janssen GM, Moustakas AK, Papadopoulos GK, Drijfhout JW, Roep BO, Koning F. van Lummel M, et al. Among authors: janssen gm. J Biol Chem. 2012 Mar 16;287(12):9514-24. doi: 10.1074/jbc.M111.313940. Epub 2011 Dec 19. J Biol Chem. 2012. PMID: 22184118 Free PMC article.
Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation.
Rosalia RA, Quakkelaar ED, Redeker A, Khan S, Camps M, Drijfhout JW, Silva AL, Jiskoot W, van Hall T, van Veelen PA, Janssen G, Franken K, Cruz LJ, Tromp A, Oostendorp J, van der Burg SH, Ossendorp F, Melief CJ. Rosalia RA, et al. Eur J Immunol. 2013 Oct;43(10):2554-65. doi: 10.1002/eji.201343324. Epub 2013 Aug 5. Eur J Immunol. 2013. PMID: 23836147 Free article.
Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.
Rombouts Y, Willemze A, van Beers JJ, Shi J, Kerkman PF, van Toorn L, Janssen GM, Zaldumbide A, Hoeben RC, Pruijn GJ, Deelder AM, Wolbink G, Rispens T, van Veelen PA, Huizinga TW, Wuhrer M, Trouw LA, Scherer HU, Toes RE. Rombouts Y, et al. Among authors: janssen gm. Ann Rheum Dis. 2016 Mar;75(3):578-85. doi: 10.1136/annrheumdis-2014-206598. Epub 2015 Jan 13. Ann Rheum Dis. 2016. PMID: 25587188
The first step of peptide selection in antigen presentation by MHC class I molecules.
Garstka MA, Fish A, Celie PH, Joosten RP, Janssen GM, Berlin I, Hoppes R, Stadnik M, Janssen L, Ovaa H, van Veelen PA, Perrakis A, Neefjes J. Garstka MA, et al. Among authors: janssen gm, janssen l. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1505-10. doi: 10.1073/pnas.1416543112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605945 Free PMC article.
Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses.
Lehmann KC, Gulyaeva A, Zevenhoven-Dobbe JC, Janssen GM, Ruben M, Overkleeft HS, van Veelen PA, Samborskiy DV, Kravchenko AA, Leontovich AM, Sidorov IA, Snijder EJ, Posthuma CC, Gorbalenya AE. Lehmann KC, et al. Among authors: janssen gm. Nucleic Acids Res. 2015 Sep 30;43(17):8416-34. doi: 10.1093/nar/gkv838. Epub 2015 Aug 24. Nucleic Acids Res. 2015. PMID: 26304538 Free PMC article.
141 results