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Page 1
Canonical autophagy does not contribute to cellular radioresistance.
Schaaf MB, Jutten B, Keulers TG, Savelkouls KG, Peeters HJ, van den Beucken T, van Schooten FJ, Godschalk RW, Vooijs M, Rouschop KM. Schaaf MB, et al. Among authors: keulers tg. Radiother Oncol. 2015 Mar;114(3):406-12. doi: 10.1016/j.radonc.2015.02.019. Epub 2015 Mar 13. Radiother Oncol. 2015. PMID: 25779723
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. J Clin Invest. 2010 Jan;120(1):127-41. doi: 10.1172/JCI40027. Epub 2009 Dec 14. J Clin Invest. 2010. PMID: 20038797 Free PMC article.
PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.
Rouschop KM, Dubois LJ, Keulers TG, van den Beucken T, Lambin P, Bussink J, van der Kogel AJ, Koritzinsky M, Wouters BG. Rouschop KM, et al. Among authors: keulers tg. Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4622-7. doi: 10.1073/pnas.1210633110. Epub 2013 Mar 7. Proc Natl Acad Sci U S A. 2013. PMID: 23471998 Free PMC article.
The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia.
Schaaf MB, Cojocari D, Keulers TG, Jutten B, Starmans MH, de Jong MC, Begg AC, Savelkouls KG, Bussink J, Vooijs M, Wouters BG, Rouschop KM. Schaaf MB, et al. Among authors: keulers tg. Radiother Oncol. 2013 Sep;108(3):529-34. doi: 10.1016/j.radonc.2013.06.015. Epub 2013 Jul 9. Radiother Oncol. 2013. PMID: 23849170
LC3/GABARAP family proteins: autophagy-(un)related functions.
Schaaf MB, Keulers TG, Vooijs MA, Rouschop KM. Schaaf MB, et al. Among authors: keulers tg. FASEB J. 2016 Dec;30(12):3961-3978. doi: 10.1096/fj.201600698R. Epub 2016 Sep 6. FASEB J. 2016. PMID: 27601442 Review.
22 results