Antibody landscape of C57BL/6 mice cured of B78 melanoma via a combined radiation and immunocytokine immunotherapy regimen.
Hoefges A, McIlwain SJ, Erbe AK, Mathers N, Xu A, Melby D, Tetreault K, Le T, Kim K, Pinapati RS, Garcia BH, Patel J, Heck M, Feils AS, Tsarovsky N, Hank JA, Morris ZS, Ong IM, Sondel PM.
Hoefges A, et al. Among authors: le t.
Front Immunol. 2023 Nov 23;14:1221155. doi: 10.3389/fimmu.2023.1221155. eCollection 2023.
Front Immunol. 2023.
PMID: 38077403
Free PMC article.
This suggests that every mouse has a unique set of antibodies produced in response to the curative therapy, creating an individual "fingerprint." Additionally, certain epitopes and proteins stand out as more immunogenic, as they are recognized by multiple mice in the immun …
This suggests that every mouse has a unique set of antibodies produced in response to the curative therapy, creating an individual "f …