Packham GK - Search Results

1

Stratifying risk of recurrence in stage II colorectal cancer using deregulated stromal and epithelial microRNAs.

Bullock MD, Pickard K, Mitter R, Sayan AE, Primrose JN, Ivan C, Calin GA, Thomas GJ, Packham GK, Mirnezami AH. Bullock MD, et al. Among authors: packham gk. Oncotarget. 2015 Mar 30;6(9):7262-79. doi: 10.18632/oncotarget.3225. Oncotarget. 2015. PMID: 25788261 Free PMC article.

2

Characterisation of the in vitro activity of the depsipeptide histone deacetylase inhibitor spiruchostatin A.

Crabb SJ, Howell M, Rogers H, Ishfaq M, Yurek-George A, Carey K, Pickering BM, East P, Mitter R, Maeda S, Johnson PW, Townsend P, Shin-ya K, Yoshida M, Ganesan A, Packham G. Crabb SJ, et al. Biochem Pharmacol. 2008 Aug 15;76(4):463-75. doi: 10.1016/j.bcp.2008.06.004. Epub 2008 Jun 20. Biochem Pharmacol. 2008. PMID: 18611394

3

MicroRNAs: key players in carcinogenesis and novel therapeutic targets.

Mirnezami AH, Pickard K, Zhang L, Primrose JN, Packham G. Mirnezami AH, et al. Eur J Surg Oncol. 2009 Apr;35(4):339-47. doi: 10.1016/j.ejso.2008.06.006. Epub 2008 Jul 21. Eur J Surg Oncol. 2009. PMID: 18644693 Review.

4

The desmoplastic reaction surrounding hepatic colorectal adenocarcinoma metastases aids tumor growth and survival via alphav integrin ligation.

Conti JA, Kendall TJ, Bateman A, Armstrong TA, Papa-Adams A, Xu Q, Packham G, Primrose JN, Benyon RC, Iredale JP. Conti JA, et al. Clin Cancer Res. 2008 Oct 15;14(20):6405-13. doi: 10.1158/1078-0432.CCR-08-0816. Clin Cancer Res. 2008. PMID: 18927279 Free PMC article.

5

MicroRNAs: critical regulators of epithelial to mesenchymal (EMT) and mesenchymal to epithelial transition (MET) in cancer progression.

Bullock MD, Sayan AE, Packham GK, Mirnezami AH. Bullock MD, et al. Among authors: packham gk. Biol Cell. 2012 Jan;104(1):3-12. doi: 10.1111/boc.201100115. Epub 2011 Dec 9. Biol Cell. 2012. PMID: 22188537 Review.

6

Pleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progression.

Bullock MD, Pickard KM, Nielsen BS, Sayan AE, Jenei V, Mellone M, Mitter R, Primrose JN, Thomas GJ, Packham GK, Mirnezami AH. Bullock MD, et al. Among authors: packham gk. Cell Death Dis. 2013 Jun 20;4(6):e684. doi: 10.1038/cddis.2013.213. Cell Death Dis. 2013. PMID: 23788041 Free PMC article.

7

FOXO3 expression during colorectal cancer progression: biomarker potential reflects a tumour suppressor role.

Bullock MD, Bruce A, Sreekumar R, Curtis N, Cheung T, Reading I, Primrose JN, Ottensmeier C, Packham GK, Thomas G, Mirnezami AH. Bullock MD, et al. Among authors: packham gk. Br J Cancer. 2013 Jul 23;109(2):387-94. doi: 10.1038/bjc.2013.355. Epub 2013 Jul 4. Br J Cancer. 2013. PMID: 23828518 Free PMC article.

8

miR-153 supports colorectal cancer progression via pleiotropic effects that enhance invasion and chemotherapeutic resistance.

Zhang L, Pickard K, Jenei V, Bullock MD, Bruce A, Mitter R, Kelly G, Paraskeva C, Strefford J, Primrose J, Thomas GJ, Packham G, Mirnezami AH. Zhang L, et al. Cancer Res. 2013 Nov 1;73(21):6435-47. doi: 10.1158/0008-5472.CAN-12-3308. Epub 2013 Aug 15. Cancer Res. 2013. PMID: 23950211 Free PMC article.

9

Molecular profiling of the invasive tumor microenvironment in a 3-dimensional model of colorectal cancer cells and ex vivo fibroblasts.

Bullock MD, Mellone M, Pickard KM, Sayan AE, Mitter R, Primrose JN, Packham GK, Thomas G, Mirnezami AH. Bullock MD, et al. Among authors: packham gk. J Vis Exp. 2014 Apr 29;(86):51475. doi: 10.3791/51475. J Vis Exp. 2014. PMID: 24836208 Free PMC article.

10

The Nrf2 transcription factor contributes to resistance to cisplatin in bladder cancer.

Hayden A, Douglas J, Sommerlad M, Andrews L, Gould K, Hussain S, Thomas GJ, Packham G, Crabb SJ. Hayden A, et al. Urol Oncol. 2014 Aug;32(6):806-14. doi: 10.1016/j.urolonc.2014.02.006. Epub 2014 May 16. Urol Oncol. 2014. PMID: 24837013

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